During the Early-Middle Ordovician, Upper Yangtze Platform experienced extensive development of a distinctive set mixed siliciclastic-carbonate deposits known as Meitan Formation. To conduct comprehensive study relationship between sedimentation and sea-level changes, Hailong section, situated at southwest margin in SW China, was selected area due to its typical sedimentary sequence. This secti...

39 40 Land skin temperature (Ts) is an important parameter in the energy exchange 41 between the land surface and atmosphere. Here hourly Ts from the Community Land 42 Model Version 4.0, MODIS satellite observations, and in-situ observations in 2003 43 were compared. Compared with the in-situ observations over four semi-arid stations, 44 both MODIS and modeled Ts show negative biases, but MODIS...

Thymidylate synthase (TS; EC 2.1.1.45) is an important cellular enzyme that converts dUMP to dTMP, which is essential for DNA biosynthesis. In addition, TS is an important cellular target for the fluoropyrimidine cytotoxic drugs that are widely used in the treatment of solid tumors. We have generated five monoclonal antibodies against human TS using a recombinant human TS enzyme. These antibodi...

BACKGROUND AND PURPOSE Transcranial Doppler ultrasound (TCD) can detect circulating microembolic signals (MES). We focused our attention on tail signs (TS), a signal associated with MES that appeared as a small reversal signal after MES on the high time resolution spectral display. We examined MES and artifacts in an animal study to determine whether TS were specific changes associated with MES...

a twenty-year-old girl was referred with tracheal stenosis (ts) which was a consequence of prolonged intubation after head injury because of previous car accident. the patient was aphasic and had normal respiration. fiberoptic bronchoscopy showed complete tracheal obstruction at second tracheal ring level. distal trachea was normal through tracheostomy tube. removal of the tracheostomy tube and...

The role of cysteine sulfhydryl residues on the RNA binding activity of human thymidylate synthase (TS) was investigated by mutating each cysteine residue on human TS to a corresponding alanine residue. Enzymatic activities of TS:C43A and TS:C210A mutant proteins were nearly identical to wild-type TS, while TS:C180A and TS:C199A mutants expressed >80% of wild-type enzyme activity. In contrast, ...

Tourette Syndrome (TS) is characterized by the presence of chronic tics. Individuals with TS often report difficulty with ignoring (habituating to) tactile sensations, and some patients perceive that this contributes to a "premonitory urge" to tic. While common, the physiological basis of impaired tactile processing in TS, and indeed tics themselves, remain poorly understood. It has been well e...

CONTEXT Tourette syndrome (TS) is a heterogeneous neuropsychiatric disorder. Chronic motor and phonic tics are central symptoms in TS patients. For some patients, tics are intractable to any traditional treatment and cause lifelong impairment and life-threatening symptoms. New therapies should be developed to address symptoms and overt manifestations of TS. Transplantation of neurogenic stem ce...

Five temperature-sensitive growth mutants of the hamster cell line BHK-21 were tested for the ability to support adenovirus 2 multiplication at 39 degrees and 33 degrees. Wild-type BHK-21 and mutants ts 422E and ts BCH yielded comparable amounts of virus at 33 degrees and 39 degrees, whereas in three other mutants, ts T22, ts T23, and ts AF8, virus production at 39 degrees was reduced to about ...