PURPOSE To identify the genetic defect of a consanguineous Portuguese family with rod-cone dystrophy and varying degrees of decreased audition. METHODS A detailed ophthalmic and auditory examination was performed on a Portuguese patient with severe autosomal recessive rod-cone dystrophy. Known genetic defects were excluded by performing autosomal recessive retinitis pigmentosa (arRP) genotypi...

PURPOSE To test the incidence of mutations in RPGR ORF15 in six families with X-linked progressive retinal degeneration (cone-rod dystrophy [XLCORD], macular or cone dystrophy) and to undertake a detailed phenotypic assessment of families in whom ORF15 mutations were identified. METHODS To amplify and sequence ORF15 in its entirety, a cloning strategy was developed. Families with mutations in...

PURPOSE Both the AccuBoost D-shaped and round applicators have been dosimetrically characterized and clinically used to treat patients with breast cancer. While the round applicators provide conformal dose coverage, under certain clinical circumstances the breast skin dose may be higher than preferred. The purpose of this study was to modify the round applicators to minimize skin dose while not...

A very common helical surface in various mechanisms is a straight closed helicoid or screw conoid, known the technical field as screw. Considering wide application of screws, there are methods their production (winding, rolling, stamping, stretching flat rings welded together on shaft). Since conoid nondevelopable, ring an approximate sweep screw, since exact does not exist. During formation tu...

Binary Fresnel zone plates (ZP) are one of the most frequently used focusing elements inplane optical schemes in micro- and nanophotonics. With a decrease diameter focal distance ZP to meso-wavelength sizes, parameters region begin be significantly influenced by features design (material, thickness, relief depth). The spatial structure spot formed near-field is investigated numerical finite (FE...

The present paper aims to study the behavior of tailor welded blanks subjected a single point incremental forming (SPIF) process from an experimental view. This was chosen deform truncated cone shapes AA1050 aluminum alloy with different thicknesses. A uniaxial tensile test performed determine mechanical characteristics alloy. Initial tests implicated use variable wall angle parts which were pr...

We theoretically study the propagation of an interacting Bose-Einstein condensate in a two-dimensional disorder potential, following principle atom laser. The constructive interference between time-reversed scattering paths gives rise to coherent backscattering, which may be observed under form sharp cone disorder-averaged angular backscattered current. As is found by numerical integration Gros...

Many recent studies show that the performance of Savonius turbines can be considerably increased by using wind deflectors. Axisymmetric deflectors are particularly interesting; they concentrate flow in all directions. This study aims to aerodynamically optimize truncated cone deflector shape through transient 3D CFD simulations sliding mesh techniques. To reduce size and thus simulation time, s...

Let {ej} be an orthonormal basis of Laplace eigenfunctions a compact Riemannian manifold (M, g). H ⊂ M submanifold and {ψk} with the induced metric. We obtain joint asymptotics for Fourier coefficients $${\left\langle {{\gamma _H}{e_j},{\psi _k}} \right\rangle _{{L^2}(H)}} = {\int_H {{e_j}\overline \psi } _k}d{V_H}$$ restrictions γhej ej to H. In particular, we sums norm-squares over spectrum $...