Abstract Funding Acknowledgements Type of funding sources: None. Relevance the problem. Anthracycline cardiotoxicity is most unfavorable form due to irreversible complications cardiovascular system caused by anthracyclines during chemotherapy (CT) breast cancer (BC). Despite fact that this type has been studied better than others, problem preventing such remains relevant day. In our study, we s...

Microspheres of Trimetazidine Hydrochloride (TZ) were prepared by coacervation method without the use of chemical cross–linking agents such as glutaraldehyde to avoid the toxic reactions and other undesirable effects of the chemical cross-linking agents. Alternatively, ionotropic gelation was employed by using sodium-tripolyphosphate (Na-TPP) as cross linking agent. Chitosan was used as polymer...