نتایج جستجو برای: trimerization

تعداد نتایج: 507  

Journal: :Journal of Investigative Dermatology 2023

Collagen XVII (ColXVII, also known as BP180, BPAg2) is a constituent of hemidesmosomes that bind epidermis to underlying layers the skin. It type II transmembrane protein with 15 extracellular collagenous domains. Juxtamembraneous non-collagenous 16th A domain (NC16A) in human ColXVII target for cleavage proteases shed from cell surface during keratinocyte migration and differentiation. The imp...

Journal: :ACS applied polymer materials 2023

Polyurethane (PU) is one of the most common and versatile polymers in many applications especially construction automotive industry where improvement thermal stability flame retardancy crucial. As polyisocyanaurate (PIR) well known to have a high decomposition temperature phosphorus motifs are usually used as retardants polymers, introduction PIR polyurethanes can lead PUs with retardancy. We i...

2014
Zhuo Li Richard Y.-C. Huang Daniel C. Yopp Travis H. Hileman Thomas J. Santangelo Jerard Hurwitz Jeffrey W. Hudgens Zvi Kelman

Proliferating cell nuclear antigen (PCNA) forms a trimeric ring that associates with and influences the activity of many proteins participating in DNA metabolic processes and cell cycle progression. Previously, an uncharacterized small protein, encoded by TK0808 in the archaeon Thermococcus kodakarensis, was shown to stably interact with PCNA in vivo. Here, we show that this protein, designated...

Journal: :Nucleic Acids Research 2005
Liusheng He Xiaoli Wu James Simone Derek Hewgill Peter E. Lipsky

The availability of protein fluorophores with appropriate spectral properties has made it possible to employ fluorescence resonance energy transfer (FRET) to assess interactions between three proteins microscopically. Flow cytometry offers excellent sensitivity, effective signal separation and the capacity to assess a large number of events, and, therefore, should be an ideal means to explore p...

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