Since the late 20th century, environmental exposure to endotoxins has been very low and type I allergic disease increased. In addition, we have increased PM2.5 other chemicals. Recently, there is concern that daily use of hygiene products containing antimicrobial substances associated with an prevalence allergies. It noted these may exacerbate our study, confirmed intratracheal administration a...

BACKGROUND Exposure to environmental chemicals, including phthalates and phenols such as parabens and triclosan, is ubiquitous within the U.S. general population. OBJECTIVE This proof-of-concept rodent study examined the relationship between oral doses of three widely used personal care product ingredients [diethyl phthalate (DEP), methyl paraben (MPB), and triclosan] and urine and serum conc...

BACKGROUND There are reports of developmental and reproductive health effects associated with the widely used biocide triclosan. OBJECTIVE Apply the Navigation Guide systematic review methodology to answer the question: Does exposure to triclosan have adverse effects on human development or reproduction? METHODS We applied the first 3 steps of the Navigation Guide methodology: 1) Specify a ...

315 than where total inhibition zones had formed. The important observation to make is that, outside of the inhibition zone, the inoculated cells multiplied to form visible colonies despite being in the triclosan vapour for up to 72 h at 22°C. This is entirely in accord with zone theory and, of course, everyday experience with diffusion susceptibility tests. It is unlikely therefore that at amb...

most active with MICs (μg/ml) against B. subtilis (1-2), MRSA (2-4), M. catarrhalis (4) and VRE (2-64). Effects on macromolecular synthesis and membrane functions were tested in B. subtilis. Pyrone I nonspecifically inhibited incorporation of radiolabeled precursors into DNA, RNA and protein within 5 minutes of drug exposure, similar to that of triclosan. Both compounds also inhibited the cellu...

reducing the bacterial level on skin, it does not eliminate all resident bacterial microflora on the skin, thus one-way pressure for the proliferation of a competing organism does not exist. Furthermore, many experts agree that normal dry skin is not a hospitable environment for the survival of gram-negative species. Long-term studies m e a s u r i n g t h e c o n s e q u e n c e s of exposure ...

Objective: to investigate the antimicrobial effects of toothpastes containing bioactive surface pre-reacted glass particles (S-PRG) on S. mutans biofilms adherence, initial colonization and maturation. Material Methods: a reference UA 159 clinical (SM6) strain were used. Bovine enamel specimens randomly allocated into groups (n=5): 0%; 1%; 5%; 20%; 30% S-PRG; positive control dentifrice (NaF+tr...

Antibiotic resistance within the community setting is an emerging public-health concern. Infection with antibiotic-resistant organisms in the community among people lacking traditional risk factors has been reported. In addition, prevalence studies have identified individuals carrying antibiotic-resistant organisms in the absence of known risk factors. These studies strongly suggest the presenc...

Urinary catheters often become encrusted and blocked by crystalline Proteus mirabilis biofilms. Results of experiments in a laboratory model of a Foley catheterised bladder infected with P mirabilis showed that when retention balloons were inflated with a solution of triclosan (10 g/L), the catheters drained freely for at least 7 days. Triclosan became impregnated throughout the silicone cathet...