BACKGROUND Prevalent herpes simplex virus type 2 (HSV-2) infection increases human immunodeficiency virus acquisition. We hypothesized that HSV-2 infection might also predispose individuals to acquire other common sexually transmitted infections (STIs). METHODS We studied the association between prevalent HSV-2 infection and STI incidence in a prospective, randomized trial of periodic STI the...

Trichomoniasis is a sexually transmitted infection (STI), caused by the protozoan parasite, Trichomonas vaginalis. Female sex workers are intensely affected infection, since they have frequent direct physical contact. The current systematic review and meta-analysis represents global prevalence of T. vaginalis in female workers. Five databases (Science Direct, Scopus, PubMed, Web Science, Google...

OBJECTIVE Trichomonas vaginalis vaginal infections are often both asymptomatic and difficult to detect by current methods. We evaluated the ability of a newly developed polymerase chain reaction (PCR) assay to identify T. vaginalis in vaginal samples from pregnant and non-pregnant women. METHODS In the 1st study, we compared the prevalence of T. vaginalis detection by PCR and culture using Di...

Trichomoniasis is a sexually transmitted infection that is highly prevalent worldwide and has been linked to preterm birth and human immunodeficiency virus acquisition. In females, trichomoniasis causes vaginitis, while in males, it is frequently asymptomatic but can be a cause of urethritis. Control efforts have been hampered by the lack of a sensitive diagnostic technique for this infection i...

Despite the declining rate of sexually transmitted diseases in developed countries, trichomoniasis is still one of the most common venereal infections. While diagnosis of this condition is commonly based on the microscopic wet-mount method, culture remains the most accurate single procedure for detecting the presence of Trichomonas vaginalis in clinical samples. In the present study, the effica...

Although many investigations into Trichomonas vaginalis Donne 1875 and vaginal trichomoniasis have been made since the organism was recognized again as a pathological entity by Hohne in 1916, problems on its pathogenicity, epidemiology and therapeutics are still left in confusion. One of the main reasons of this confusion appears that the bacteria free cultivation of this organism has not been ...

Mollicutes are the smallest and simplest self-replicating microorganisms. Despite the minimal genome and apparent lack of complexity, mycoplasmas show a high degree of adaptation to the most diverse environments. Mycoplasma hominis is a human sexually transmitted mycoplasma which is able to establish a biological association with Trichomonas vaginalis, a pathogenic flagellated protist. M. homin...

Trichomonas vaginalis PCR using reagents from a commercially available assay for Chlamydia trachomatis and Neisseria gonorrhoeae was evaluated for detection of infection in women and men attending a sexually transmitted disease clinic. Evaluations included three primer sets, endocervical swabs, vaginal swabs and urine, and various storage conditions. The TVK3/TVK7 primer set was optimal in our ...

background: metronidazole, a 5-nitroimidazole derivative, is the main antitrich­omonal agent of  choice   for   treatment  of t richomoniasis . since 1962, s ome cases of treatment failure with metronidazole have been reported and recently drug re­sistance is now on the rise in the world. this study was aimed to determine current susceptibility of iranian isolates of trichomonas vaginalis to me...