Cancer remains an outstanding cause of global morbidity and mortality, despite intensive research and unprecedented insights into the basic mechanisms of cancer development. A plethora of clinical and experimental evidence suggests that cancers from individual patients are likely to be molecularly heterogeneous in their use of distinct oncogenic pathways and biological programs. Efforts to sign...

1. Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. 2. Departamento de Educação Médica. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal. 3. Cochrane Portugal. Lisboa. Portugal.  Autor correspondente: António Vaz-Carneiro. [email protected] Recebido: 03 de dezembro de 2016 Aceite: 04 de dezembro de 2016 | ...

Considering the possibility of unexpected situations, the authorities feel the necessity of keeping certain sub systems or components of aircraft under continuous scrutiny. Accordingly, sensors in flight control systems are considered as one of the crucial components of the system. The failure to detect faults is quite likely to cause very serious problems, which makes it vital to carry out eff...

introduction: nowadays, the widespread distribution of hospital information systems (his) in healthcare institutions requires professional evaluation to assess the practical usefulness of these applications. nursing staff are the largest group of staff in a hospital and play an important role in the adoption and evaluation of hiss. methods: this was a descriptive, analytic, cross-sectional stud...

introduction: in spite of the vast improvement in the area of mental health care delivery in this country, very little attention has been given to the mental health registry. considering the absence of an appropriate national mental health registry system in iran, the purpose of the present study was to formulate a preliminary model for mental health registry in iran. methods: in this comparati...

background: conventional health, safety and environment (hse) are a widely used approach to enhance availability and efficiency of complex systems. the integrated hsee system is defined however as integration of conventional hse with ergonomics approach. the presented hsee system introduces a unique, effective and systemic mechanism, which integrates the structure of the human and organizationa...

background and objectives: evaluation has an important role in software development. quality is considered in the evaluation of information systems, which depends on usability, availability, validity, compatibility, and response time. this research was performed with the aim of determining the usability of hospital information systems according to the 7 principles of isometric 9241, part 10. me...