Introduction: Individuals who participate in high running volumes are at risk of sustaining tibial stress injuries. Increased acceleration during is a potential factor for developing Modified technique and/or equipment can potentially alter accelerations to reduce load and placed on the tibia. Numerous interventions (e.g. changes foot strike cadence; wearing minimalist shoes) modify loads have ...

In previous research on treadmills, the main focus has been comparing physiological differences induced by running treadmill decks and other exercise surfaces, with relatively little mechanical properties of decks. Reducing sports injuries is a common desire runners, which may be closely related to muscle activity. Obviously, play an important role in this process. Muscle activity was evaluated...

OBJECTIVE To understand the changes of femoral cartilage in response to treadmill running with different intensities in the hope of differentiating "moderate" and "strenuous" running in a rat model. METHOD A total of 24 male Wistar rats were randomly assigned into groups of sedentary (SED), low-intensity running (LIR), medium-intensity running (MIR), and high-intensity running (HIR). Rats in ...

Sirt3, a member of the sirtuin family, is known to control cellular mitochondrial function. Furthermore, because sirtuins require NAD for their deacetylase activity, nicotinamide phosphoribosyltransferase (Nampt), which is a rate-limiting enzyme in the intracellular NAD biosynthetic pathway, influences their activity. We examined the effects of exercise training and normal postural contractile ...