نتایج جستجو برای: transgenics

تعداد نتایج: 784  

Journal: :The Journal of Experimental Medicine 1990
L A Dent M Strath A L Mellor C J Sanderson

Experiments in vitro suggest that although interleukin 5 (IL-5) stimulates the late stages of eosinophil differentiation, other cytokines are required for the generation of eosinophil progenitor cells. In this study transgenic mice constitutively expressing the IL-5 gene were established using a genomic fragment of the IL-5 gene coupled to the dominant control region from the gene encoding huma...

Journal: :Current Biology 2013
Raymond Teck Ho Lee Jean Paul Thiery Thomas J. Carney

Figure 1. Fin osteoblasts derive from late immigrating paraxial mesoderm. (A,B) Adult (90 dpf) sox10:Cre; ubi:switch transgenics showing derivatives in the fin derived from neural crest and sox10 expressing cells. Lateral view of wholemount fin, immunostained to detect mCherry, indicates labelled cells running along the fin rays (A). Superimposing on a brightfield image demonstrates that these ...

2015
Stephanie Ascough Rebecca J. Ingram Karen K. Y. Chu Julie A. Musson Stephen J. Moore Theresa Gallagher Les Baillie Ethel D. Williamson John H. Robinson Bernard Maillere Rosemary J. Boyton Daniel M. Altmann

Anthrax is an endemic infection in many countries, particularly in the developing world. The causative agent, Bacillus anthracis, mediates disease through the secretion of binary exotoxins. Until recently, research into adaptive immunity targeting this bacterial pathogen has largely focused on the humoral response to these toxins. There is, however, growing recognition that cellular immune resp...

Journal: :Revista chilena de nutrición 2021

The supply of food products that present adequate nutritional quality is extremely important for maintaining the health population. Thus, different techniques have been used to obtain biofortified foods, with aim combating malnutrition caused by absence essential micronutrients, especially in poorest populations. This review presents an overview biofortification, emphasis on orange-flesh sweet ...

Journal: :Molecules and cells 2004
Sang-Choon Lee Kyung-Won Huh Kyungsook An Gynheung An Seong-Ryong Kim

The gene encoding C-repeat/dehydration-responsive element binding factor 1 (CBF1/DREB1b) of Arabidopsis was introduced into rice (Oryza sativa L.) under the control of the maize ubiquitin promoter. Its incorporation and expression in transgenic rice plants were confirmed by DNA and RNA gel-blot analyses. Cold tolerance in the transgenics was not significantly different from that of the wild-typ...

Journal: :Frontiers in bioscience : a journal and virtual library 1998
G E Homanics J J Quinlan R M Mihalek L L Firestone

Genetically engineered animals (e.g., transgenics, gene knockouts, gene knockins) are being utilized with increasing frequency to investigate the mechanisms of action of alcohol and anesthetics. By creating and analyzing animals that harbor precise, preplanned changes in candidate genes, researchers are rapidly making progress toward uncovering how these drugs exert their effects on the central...

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