نتایج جستجو برای: transcriptase
تعداد نتایج: 21795 فیلتر نتایج به سال:
Here, we describe an HIV-infected patient with pretreatment resistance to raltegravir, nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors and protease inhibitors, and the ultimate ability to achieve viral suppression. Pretreatment integrase resistance testing is not routinely performed because transmitted integrase mutations conferring resistance to ral...
We applied an efficient method to characterize the relative fitness levels of multiple nonnucleoside reverse transcriptase (NNRTI)-resistant HIV-1 variants by simultaneous competitive culture and 454 deep sequencing. Using this method, we show that the Y181V mutation in the HIV-1 reverse transcriptase in particular confers a clear selective advantage to the virus over 14 other NNRTI resistance ...
Abbreviations: CCR: Chemokine Co-receptor; CMV: Cytomegalovirus; CTL: Cytotoxic Lymphocytes; FIPV: Feline Infectious Peritonitis virus; HBV/HCV: Hepatitis B/C Virus; HIV/ AIDS: Human Immunodeficiency Virus/ Acquired Immunodeficiency Syndrome; HSV: Herpes Simplex Virus; JEV: Japanese Encephalitis Virus; MS: Mass Spectrometry; NK: Natural Killer Cells; NMR: Nuclear Magnetic Resonance; NRTI: Nucle...
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