background: in patients with acute stroke and middle cerebral artery (mca) stenosis, microembolic signals (mes) can predict further cerebral ischemia. therefore, this study was designed to evaluate the prevalence of mes by transcranial doppler (tcd) in patients with mca stenosis under treatment of aspirin or clopidogrel. methods: a randomized clinical trial was performed on 40 patients with acu...

background: the aim of this study is to determine the frequency of intracranial artery stenosis in patients with acute ischemic stroke in iran. methods: a total of 169 patients with acute ischemic stroke were eligible to participate and were enrolled in this study from january 2012 to february 2013. all the patients were admitted to the nemazee ‎hospital, affiliated to shiraz university of medi...

BACKGROUND AND PURPOSE The differentiation between the Alzheimer and multi-infarct types of dementia may still be equivocal considering clinical criteria, neuropsychological tests, and imaging techniques. Cerebral microangiopathic alterations underlying multi-infarct dementia should allow the characterization of dementia subgroups. METHODS Patients with a diagnosis of multi-infarct dementia (...

1.Near-infrared (IR) spectroscopy is based on the relative transparency of skin, skull and brain to the light in the near-IR region (700-1100 nm) and on the oxygen-dependent tissue absorption changes of haemoglobin.2. We evaluated the most relevant factors (reproducibility, venous return, age and sex) that might affect reliability of near-IR spectroscopy to test CO2 cerebrovascular reactivity.3...

OBJECTIVE To investigate the role of prophylactic hyperdynamic postoperative fluid therapy in preventing delayed ischemic neurological deficits attributable to cerebral vasospasm. METHODS We designed a prospected, randomized, controlled study and included 32 patients with subarachnoid hemorrhage. Sixteen patients received hypervolemic hypertensive hemodilution fluid therapy; the other 16 pati...

BACKGROUND AND PURPOSE Digital subtraction angiography is the reference standard technique to evaluate intracranial vascular anatomy and used on the endovascular treatment of vascular diseases. A dedicated optical flow-based algorithm was applied to DSA to measure arterial flow. The first quantification results of internal carotid artery flow validated with Doppler sonography are reported. MA...

BACKGROUND AND PURPOSE Atherothrombotic disease of the middle cerebral artery (MCA) frequently occurs in Asian populations. This abnormality can be noninvasively assessed with transcranial Doppler sonography (TCD) and computed tomographic angiography (CTA). To our knowledge, the usefulness of TCD sonography compared with CTA in the diagnosis of nonembolic MCA disease has not been studied. MET...

Venous system can be classified as pulmonary veins, systemic veins and venous sinuses that are present only within the skull. Cerebral venous system is divided into two main parts, the superficial and the deep system. The main assignment of veins is to carry away deoxygenated blood and other maleficient materials from the tissues towards the heart. Veins have thinner walls and larger lumina tha...