The measurement of cellular traction forces on soft elastic substrates has become a standard tool for many labs working on mechanobiology. Here we review the basic principles and different variants of this approach. In general, the extraction of the substrate displacement field from image data and the reconstruction procedure for the forces are closely linked to each other and limited by the pr...

THE OBJECTIVE OF THIS STUDY WAS TO COMPARE THE EFFECTIVENESS OF TWO COMPILED PHYSIOTHERAPY PROGRAMS: one including forceful traction mobilizations, the other including traction with unknown force, in patients with hip disability according to ICF (the International Classification of Functioning, Disability and Health, 2001; WHO), using a block randomized, controlled trial with two parallel treat...

We develop here a microfabrication compatible force measurement technique termed as ultrasoft polydimethylsiloxane-based traction force microscopy (UPTFM). This technique is devised for mapping the cellular traction forces imparted on the adhering substrate, so as to depict the physiological state of the cells surviving in the micro-confinement. We subsequently integrate the technique with a mi...

From biofilm and colony formation in bacteria to wound healing and embryonic development in multicellular organisms, groups of living cells must often move collectively. While considerable study has probed the biophysical mechanisms of how eukaryotic cells generate forces during migration, little such study has been devoted to bacteria, in particular with regard to the question of how bacteria ...