Aim. Serological indicators of organ function can reveal intrinsic links between different organs. The present study aimed to determine the correlations of serum indicators for gastric and extragastric function. Methods. A total of 823 individuals were enrolled. Data on indicators reflecting blood lipids, blood glucose, indexes of stomach, kidney, liver, and thyroid function, and H. pylori IgG ...

PURPOSE To observe the short-term dynamic change in serum CXC chemokine ligand-10 (CXCL10) levels in patients with Graves' disease (GD) before and after iodine therapy and to analyze the relationship between CXCL10 levels and clinical disease indices. METHODS ELISA was used to determine serum levels of CXCL10 in 43 patients with GD shortly before radioiodine therapy and on days six, 14, and 6...

Background Hashimoto’s thyroiditis (HT) is an organ-specific autoimmune disease that not rare in RA. Hypothyroidism caused by HT can affect the prognosis and quality of life patients with RA [1]. Many studies showed immune cells play a critical role [2-3]. However, alterations lymphocyte subsets are unclear. Objectives This study aimed to assess absolute numbers proportions peripheral investiga...

recently, several patients have been reported with various signs of encephalopathy and high thyroid antibody levels together with good responsiveness to glucocorticoid therapy. despite the various clinical presentations, these cases have been termed “hashimoto encephalopathy” (he). although all of the pathogenic components have not yet been clearly elucidated, it is believed that brain vasculit...

about 25-50% of graves' disease (gd) patients develop thyroid eye diseases, which is associated with inflammatory process and abnormalities in the levels of several cytokines in orbital tissues in gd.  the aim of this study was to determine the th1 and th2 serum cytokines in patients with gd with or without ophthalmopathy. serum  levels of  cytokines  and  autoantibodies  including interferon-g...

BACKGROUND AND OBJECTIVE The upper limit of TSH reference level is controversial. The purpose of our study was to determine TSH reference values in a Mexican population in accordance with the National Academy of Clinical Biochemistry (NACB) criteria and in correlation with thyroid ultrasound (US) examination. PATIENTS AND METHODS The study was conducted in volunteers with no known thyroid dis...

OBJECTIVE Autoimmune thyroid disease (AITD) is an organ-specific disorder due to the interplay between environmental and genetic factors. Toll-like receptors (TLRs) are pattern recognition receptors expressed abundantly on monocytes. There is a paucity of data on TLR expression in AITD. The aim of this study was to examine TLR expression, activation, ligands, and downstream signaling adaptors i...