In the present study, different in situ hydrogel formulations of docetaxel (DTX) based on biocompatible polymers such as Hyaluronic Acid (HA), poloxamer-407, chitosan and gellan gum were formulated to increase its therapeutic efficacy reduce toxicity. DTX was loaded nanovesicles (20 mg/mL equivalent commercial strength) further incorporated into bases possess a dual rationale protection against...