Contractor selection is one of the most important aspects in construction contract. This paper suggests importance of various multi criteria decision making models for contractor selection problem in Indian context. The study includes identifying the different criteria for bid evaluation and the means by which different decision making models may be used to evaluate the contractors with respect...

An Improvement of Extend TOPSIS (IE-TOPSIS) method is presented for Armament System of Systems (ASoS) selection. In this paper, ASoS selection problem is a multiple criteria decision-making problem. Because determining the specific value of the attribute for each ASoS is difficult, the criteria score is considered as interval vague value. The IETOPSIS method can deal with the interval data valu...

Supplier selection, in real situation, is affected by several qualitative and quantitative factors and is one of the most important activities of purchasing department. Since at the time of evaluating suppliers against the criteria or factors, decision makers (DMS) do not have precise, exact and complete information, supplier selection becomes more difficult. In this case, Grey theory helps us ...

To explain the pathophysiological significance of endogenous atrial natriuretic polypeptide (ANP) in the development of hypertension, we examined the effect of chronic, repetitive administrations of MAb raised against a-rat ANP in two rat models of hypertension, spontaneously hypertensive rats of the stroke prone substrain (SHR-SP), and deoxycorticosterone acetate (DOCA)-salt rats. Weekly intra...

To evaluate the role of extra-atrial atrial natriuretic peptide (ANP) in volume and blood pressure regulation, the plasma, atrial, ventricular, and hypothalamic levels of immunoreactive atrial natriuretic peptide (IR-ANP) were measured simultaneously in the spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) at the ages of 2, 6, and 12 months. Plasma IR-ANP in the 12-month-old, co...

Atrial secretion of atrial natriuretic peptide (ANP) has been shown to be regulated by atrial workload. Although modulating factors for the secretion of ANP have been reported, the role for intracellular Ca(2+) on the secretion of ANP has been controversial. The purpose of the present study was to define roles for L- and T-type Ca(2+) channels in the regulation of ANP secretion in perfused beat...

This study investigated the hypothesis that atrial natriuretic peptide (ANP) responses are mediated by particulate guanylate cyclase in the pulmonary vascular bed of the cat. When tone in the pulmonary vascular bed was raised to a high steady level with the thromboxane mimic U-46619, injections of ANP caused dose-related decreases in lobar arterial pressure. After administration of HS-142-1, an...

The main active form of atrial natriuretic peptide (ANP) in the circulation is alpha ANP(1-28) [gamma-ANP(99-126)], although some active and inactive metabolites are also though to be present. Some immunoassays for alpha ANP reportedly detect inactive metabolites, as determined by their comparison with results by receptor assay, which would lead to misleading results for alpha ANP(1-28) measure...

This study simplifies the complicated metric distance method [L.S. Chen, C.H. Cheng, Selecting IS personnel using ranking fuzzy number by metric distance method, Eur. J. Operational Res. 160 (3) 2005 803–820], and proposes an algorithm to modify Chen’s Fuzzy TOPSIS (Technique for Order Preference by Similarity to Ideal Solution) [C.T. Chen, Extensions of the TOPSIS for group decision-making und...

TOPSIS is a multiple criteria method to identify solutions from a finite set of alternatives based upon simultaneous minimization of distance from an ideal point and maximization of distance from a nadir point. TOPSIS can incorporate relative weights of criterion importance. This paper reviews several applications of TOPSIS using different weighting schemes and different distance metrics, and c...