BACKGROUND Quality of life is recognized as an important additional outcome measure in clinical trials and health economic evaluations. The EQ-5D is an important generic health outcome instrument often used for economic evaluations as a complement with disease-specific outcome measures. In this study quality of life data was assessed using the EQ-5D-Y (new EQ-5D version for children and adolesc...

BACKGROUND Economic evaluations of healthcare interventions increasingly measure outcomes using quality-adjusted life years (QALYs). The SF-6D and the EQ-5D are alternative ways of generating utility scores for use in QALY estimations, but it is unclear which is most sensitive to change in psychiatric symptom severity. There are also limited data on the sensitivity of these measures to changes ...

BACKGROUND The UK National Institute for Health and Clinical Excellence (NICE) has recommended that cost-effectiveness analysis includes the EQ-5D; however, this is often not implemented in the area of mental health. AIMS To assess the appropriateness of using the EQ-5D to measure improvements in mental health. METHOD Seventy-seven participants with psychosis were rated according to the EQ-...

We discuss a formal many-valued logic called EQlogic which is based on a recently introduced special class of algebras called EQ-algebras. The latter have three basic binary operations (meet, multiplication, fuzzy equality) and a top element and, in a certain sense, generalize residuated lattices. The goal of EQ-logics is to present a possible direction in the development of mathematical logics...

BACKGROUND A near-universal finding internationally is that patient valuations of their own health, represented using the EQ-5D system, are mostly higher than general population valuations of the same EQ-5D states. This paper investigates whether this result also applies to New Zealand. Despite the EQ-5D's widespread use for cost-utility analysis in New Zealand, in particular by the Pharmaceuti...

BACKGROUND Although a five level version of the widely-used EuroQol 5 dimensions (EQ-5D) instrument has been developed, population norms are not yet available for Australia to inform the future valuation of health in economic evaluations. The aim of this study was to estimate HrQOL normative values for the EQ-5D-5L preference-based measure in a large, randomly selected, community sample in Sout...

We incorporate equations in binary decision diagrams (BDD). The resulting objects are called EQ-BDDs. A straightforward notion of ordered EQ-BDDs (EQ-OBDD) is de ned, and it is proved that each EQ-BDD is logically equivalent to an EQ-OBDD. Moreover, on EQ-OBDDs satis ability and tautology checking can be done in constant time. Several procedures to eliminate equality from BDDs have been reporte...

BACKGROUND Prior to using a generic patient-reported outcome measure (PRO), the measure should be validated within the target population. The purpose of the current study was to validate two generic measures in patients with type 2 diabetes. METHODS Patients with type 2 diabetes in Scotland and England completed two generic measures: EQ-5D and Psychological General Well-Being Index (PGWB). Tw...

BACKGROUND We aimed to evaluate health status and associated factors in community-dwelling elderly in the Netherlands. METHODS Participants from a placebo-controlled double-blind randomized controlled trial conducted in the Netherlands were invited at the time of enrolment to participate in this study. Data were collected on comorbidities, socio-demographic background and health status, using...