نتایج جستجو برای: tmprss2

تعداد نتایج: 875  

Journal: :Molecular and Cellular Endocrinology 2018
Eugenio Zoni Sofia Karkampouna George N. Thalmann Marianna Kruithof-de Julio Martin Spahn

Prostate cancer (PCa) is the most common malignancy detected in males and the second most common cause of cancer death in western countries. The development of the prostate gland, is finely regulated by androgens which modulate also its growth and function. Importantly, androgens exert a major role in PCa formation and progression and one of the hypothesized mechanism proposed has been linked t...

2016
Zheng Zhang Rainer B Lanz Lijuan Xiao Lei Wang Sean M Hartig Michael M Ittmann Qin Feng Bin He

The TMPRSS2-ERG fusion occurs in approximately 50% of prostate cancer (PCa), resulting in expression of the oncogenic ERG in the prostate. Because ERG is a transcriptional activator, we hypothesized that ERG-regulated genes contribute to PCa development. Since microRNA (miRNA) has crucial functions in cancer, we searched for miRNAs regulated by ERG in PCas. We mined published datasets based on ...

Journal: :Journal of human genetics and genomics 2021

: In December 2019, the new virus, COVID-19, emerged and led to a pandemic respiratory acute disease. Almost all countries have experienced different rates of morbidity mortality. These differences can be attributed factors such as diagnostic test capacity for COVID-19 health system efficiency. Besides between related management, patients represent diverse range clinical symptoms, from outpatie...

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