This study reports on the application of the MOSkinTM dosimeter in MSCT imaging for the real-time measurement of absorbed organ point doses in a tissue-equivalent female anthropomorphic phantom. MOSkinTM dosimeters were placed within the phantom to measure absorbed point organ doses for 2 commonly applied clinical scan protocols, namely the renal calculus scan and the pulmonary embolus scan. Me...

Abstract. Interventional guidance systems require surgical navigation systems to register different tools and technologies together. Standard navigation systems have drawbacks leading to target registration errors (TRE) of around 3mm. This project introduces the photoacoustic (PA) effect as a direct 3D ultrasound (US) to video registration method. We demonstrate its feasibility on both a synthe...

Iron is a trace mineral that plays a vital role in the human body. However, absorbing and accumulating excessive iron in body organs (iron overload) can damage or even destroy an organ. Even after many decades of research, progress on the development of noninvasive and low-cost tissue iron detection methods is very limited. Here we report a recent advance in a room-temperature ultrasensitive bi...

Brass mesh bolus has been shown to be an acceptable substitute for tissue-equivalent bolus to increase superficial dose for chest wall tangent photon radiotherapy. This work investigated the increase in surface dose, the change in the dose at depth, and the safety implications of higher energy photon beams when using brass mesh bolus for postmastectomy chest wall radiotherapy. A photon tangent ...

Megavoltage, cone-beam computed tomography (MV CBCT) employing an electronic portal imaging device (EPID) is a highly promising technique for providing soft-tissue visualization in image-guided radiotherapy. However, current EPIDs based on active matrix flat-panel imagers (AMFPIs), which are regarded as the gold standard for portal imaging and referred to as conventional MV AMFPIs, require high...

Introduction: This study investigates to what extent the computed dose received by lung tissue in a commercially available treatment planning system (TPS) for 192Ir high-dose-rate breast brachytherapy is accurate in view of tissue inhomogeneities and presence of ribs. Materials and Methods: A CT scan of the breast was used to construct a patient-equivalent phantom in the clinical treatment plan...

A bone tissue phantom prototype allowing to test, in general, optical flowmeters at large interoptode spacings, such as laser-Doppler flowmetry or diffuse correlation spectroscopy, has been developed by 3D-stereolithography technique. It has been demonstrated that complex tissue vascular systems of any geometrical shape can be conceived. Absorption coefficient, reduced scattering coefficient an...