Although vitamin E deficiency in ruminants results in conspicuous heart disease, a similar deficiency state in primates appears to spare the heart, even when other systems are affected. No heart disease in man has been related to a vitamin E deficiency. The pharmacologic use of vitamin E in doses 10 to 50 times the daily requirement was recommended in 1947 for the treatment of a variety of card...

AIM The purpose of this study was to describe two challenging cases of septic cavernous sinus thrombosis (CST), which presented with vastly different clinical signs and symptoms. METHODS We present two cases of CST with markedly differing clinical presentations, medical comorbidities, and degree of impairment. Initial imaging of each patient failed to show thromboembolic disease. RESULTS Bo...

A 34-year-old female patient presented with fever and right flank pain ten days after uncomplicated vaginal delivery. CT examination revealed right ovarian vein thrombosis and methicillin-resistant Staphylococcus aureus (MRSA) was isolated from blood cultures. No other source of bacteremia was found. Antibiotic therapy and anticoagulation with enoxaparin were instituted. Fourteen days after adm...

SUPPURATION in the adnexa of the eye is always serious, as we can never be sure that the seemingly harmless stye may not cause a retrobulbar phlegmon, and subsequently cavernous sinus thrombophlebitis may develop on account of the rich anastomoses between the two areas. Every ophthalmologist can remember more than one case in which it was impossible to save the patient' life. Until recently, th...

A 28-year-old previously healthy man presented with a 5-year history of recurrent painful subcutaneous nodules in varying locations, including both legs, left foot, hand, and groin. He initially spontaneously developed a 1-cm nodule in his right calf that progressed over 2 days to 4 cm in length and then resolved, with the entire episode lasting 5 days. The patient reported >10 similar events o...

A 35 year old man presented with the sudden onset of left leg pain and swelling. Empirical anticoagulation for presumed deep vein thrombophlebitis was followed by acute worsening of symptoms. On further evaluation the patient was found to have a ruptured Baker's cyst and an acute posterior compartment syndrome.

The cardiovascular system is involved in 5% of the cases of Behçet's disease. Thrombophlebitis. aneurysm in arteries, pericarditis, myocarditis, valvular disease, ventricular arrhythmia, and conduction system disorders may occur. A case of Behçet's disease with complete proximal atrioventricular block is presented.

We describe a patient who developed daptomycin-resistant, methicillin-resistant Staphylococcus aureus (MRSA) during an episode of presumed septic thrombophlebitis of the portal vein. Although daptomycin is an alternative agent for treatment of drug-resistant gram-positive bacterial infections, development of resistance during prolonged use may occur with MRSA bacteremia from a persistent focus.

Fusobacterium species are well described as the causative pathogen in Lemierre's syndrome, a suppurative thrombophlebitis of the jugular vein. However, they are less recognized for a unique variant of Lemierre's syndrome presenting with invasive intraabdominal infection and associated portal vein thrombosis. We describe a case of Fusobacterium nucleatum with hepatic abscess and septic pylephleb...

We report a case of Lemierre's syndrome due to Fusobacterium nucleatum in a previously healthy 19-year-old male. This is the first case report of Lemierre's syndrome due to thrombophlebitis of the external jugular vein. The patient had a rapid clinical response to anticoagulation and antibiotics, as supported by anecdotal evidence.