The 23-kDa piroplasm membrane protein of Theileria orientalis (p23) is an immunogenic protein expressed during the intraerythrocytic stage of the parasite; its function, however, remains unclear. To evaluate the host factor or factors that interact with p23, we examined the binding of p23 to components of the host cell surface. Recombinant p23 protein of the Ikeda genotype failed to bind to bov...

PURPOSE Streptococcus mutans has been implicated as the major causative agent of dental caries. Although restorative treatment for caries is thought to temporarily eliminate the carious challenge, there are few reports of alterations in salivary mutans streptococci (MS) numbers and no reports of changes in salivary IgA antibody to S. mutans following restorative treatment. METHODS This study ...

We tried to develop an experimental system for quantifying piroplasm transmission in Theileria sergenti infection using a SCID mouse model, of which red blood cells (RBC) had been substituted with bovine (Bo). A mouse hybridoma cell producing antibody against Holstein RBC was established for distinguishing Holstein RBC from Japanese Black RBC by a immuno-staining method. T. sergenti piroplasms ...

The histone-like proteins (HU) belong to a family of DNA architectural proteins that stabilize nucleoprotein complexes. We found a putative HU protein (TgGlmHMM_3045) in Toxoplasma gondii genome that was homologous to the bacterial HU protein. This putative sequence was located in the scaffold TGG_995361 of the chromosome 10. The sequence included the prokaryotic bacterial histone-like domain, ...

background: ovine anaplasmosis and theileriosis are important tick-borne diseases of sheep and goats which are distributed in the tropical and subtropical areas of the world. objectives: this study was performed to assess hematological status in sheep naturally infected with anaplasma and theileria spp. to clarify the pathogenic aspects of various species involved in ovine anaplasmosis and thei...

In order to develop a method for detecting and identification of Theileria annulata, the specific primers from the major merozoite-piroplasm surface antigen sequence of Theileria (Tams1) were used to detect the T. annulata by nested-PCR technique. The assay provides a valuable tool for the identification of Theileria annulata directly from clinical samples and enables determination of the infec...

tropical theileriosis is caused by infection of bovine myeloid mononuclear cells (monocytes and macrophages) and lymphoid cells (b lymphocytes) as well as red blood cells by the protozoan parasite theileria annulata. the disease is transmitted by ticks of the genus hyalomma. the clinical signs of theileriosis in stages appear from mild symptoms to serious, including fever and anemia to severe i...

Anti-piroplasm drugs currently on the market have proven toxicity to host and parasite resistance. Plants are possible sources of novel drugs. Subsequently, a strategy should be used find new anti-piroplasm agents that both effective safe. In present study, we evaluated effect turmeric (Curcuma longa) methanolic extract in vitro growth Babesia (B.) bovis, B. divergens, caballi, Theileria (T.) e...