β-Diguetoxin-Dc1a (Dc1a) is a toxin from the desert bush spider Diguetia canities that incapacitates insects at concentrations that are non-toxic to mammals. Dc1a promotes opening of German cockroach voltage-gated sodium (Nav) channels (BgNav1), whereas human Nav channels are insensitive. Here, by transplanting commonly targeted S3b-S4 paddle motifs within BgNav1 voltage sensors into Kv2.1, we ...

The focus of the research project presented in this article is on the structure of the life stories of elderly people living in old age homes and its relationship to wellbeing or quality of life and the quality of the caring relationship. In an experimental design, we are testing the hypothesis that intervention with narrative methods has a positive effect on existential well-being and quality ...

due to universal importance of tabriz carpet art and presence of specific indicators and motifs in tabriz carpet art and its potentials, existence of architectural site for representing this art as carpet art museum in tabriz is necessary. the site of this project is located adjacent to tabriz blue mosque near the museum historical site. it is essential to consider the historical elements and c...

The unique contribution of the Israeli high-risk study is the comparison of children at risk for schizophrenia with matched controls in two settings: those raised in nuclear families in towns, and those raised in children's houses on kibbutzim. Such a design makes possible direct comparison of genetic and environmental effects on the psychosocial functioning of a group of high-risk children, ov...

an amalgamation of ancient mythological and linguistic features from ghabrestan tepe, this article is disposed to introduce some of the oldest findings especially about the then prevailing myths. it can possibly be said that the oldest motifs carved by men, on bones, stones or on cave walls have been the depictions of myths related to homo sapiens; however, even after the lapse of thousands of ...