During this study the application of Natrolite zeolite was investigated as a solid acid catalyst for efficient preparation of 5substituted 1H-tetrazole derivatives. Excellent yields of products were obtained with a wide range of substrates. After completion of the reaction, the catalyst was recovered by filtration and reused several times with only a slight decrease of activity observed under t...

New tetrazole analogues with bio-active cores have been synthesized by a novel synthetic methodology. The synthesized compounds were characterized using FT-IR, MS, elemental analysis, H, C and HSQC NMR spectroscopic techniques. The synthesized compounds were screened for their antibacterial activities against Staphylococcus aureus, Escherichia coli, Vibreo cholerae, Pseudomonas aeruginosa and K...

The decomposition of 5-benzhydryl-1H-tetrazole in an N-methyl-2-pyrrolidone/acetic acid/water mixture was investigated under a variety of high-temperature reaction conditions. Employing a sealed Pyrex glass vial and batch microwave conditions at 240 °C, the tetrazole is comparatively stable and complete decomposition to diphenylmethane requires more than 8 h. Similar kinetic data were obtained ...