Tetanus is a potentially fatal infection. Approximately 100 cases are reported in Japan each year; however, little is known about its clinical course and outcomes in the current era of treatment. We herein report three cases of tetanus in elderly patients who survived after mechanical ventilation and intensive care. These patients, together with six other similar cases, had a median weaning per...

Tetanus and diphtheria vaccines are of special concern in adolescents because boosters are necessary for adequate maintenance of protection and are often omitted. We assessed serum levels of tetanus and diphtheria antibodies in adolescents and their association with vaccination status. From May to October 2001, we evaluated the vaccination records of 208 adolescents aged 10 to 20 years in São P...

group with otorrhea (26.3%). The average incubation period – recorded in 78 cases where the information was available – was 13.4 days with maximum deaths observed in cases with incubation period < 7 days. Besides short incubation period, onset of spasms within 24 hours of illness, severe spasms and temperature >99 oF within 24 hours of admission were the factors associated with grave prognosis....

OBJECTIVE This study aimed to estimate the incremental cost-effectiveness of supplementary immunization activities to prevent neonatal tetanus in the Loralai district of Pakistan. The supplemental immunization activities were carried out in two phases during 2001-03. METHODS A state-transition model was used to estimate the effect of routine vaccination with tetanus toxoid as well as vaccinat...