نتایج جستجو برای: terpenoids

تعداد نتایج: 2568  

Journal: :Bulletin of the Chemical Society of Japan 1987

2012
Sotirios C. Kampranis Antonios M. Makris

Technological developments over the past century have made microbes the work-horses of large scale industrial production processes. Current efforts focus on the metabolic engineering of microbial strains to produce high levels of desirable end-products. The arsenal of the contemporary metabolic engineer contains tools that allow either targeted rational interventions or global screens that comb...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2016
Patrick Schrepfer Alexander Buettner Christian Goerner Michael Hertel Jeaphianne van Rijn Frank Wallrapp Wolfgang Eisenreich Volker Sieber Robert Kourist Thomas Brück

Class I terpene synthases generate the structural core of bioactive terpenoids. Deciphering structure-function relationships in the reactive closed complex and targeted engineering is hampered by highly dynamic carbocation rearrangements during catalysis. Available crystal structures, however, represent the open, catalytically inactive form or harbor nonproductive substrate analogs. Here, we pr...

2017
Abdul Fatah A. Samad Nazaruddin Nazaruddin Muhammad Sajad Jaeyres Jani Abdul Munir Abdul Murad Zamri Zainal Ismanizan Ismail

Persicaria minor (kesum) is an important medicinal plant and commonly found in southeast countries; Malaysia, Thailand, Indonesia, and Vietnam. This plant is enriched with a variety of secondary metabolites (SMs), and among these SMs, terpenoids are in high abundance. Terpenoids are comprised of many valuable biomolecules which have well-established role in agriculture and pharmaceutical indust...

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