It has been proposed that with the appropriate models, instrumented indentation test (IIT) data can be reduced to yield the uniaxial stress–strain behavior of the test material. However, very little work has been done to directly compare the results from uniaxial tension and spherical indentation experiments. In this work, indentation and uniaxial tension experiments have been performed on the ...

Erythrocytes are responsible for transporting oxygen to tissue and are essential for the survival of almost all vertebrate animals. Circulating erythrocyte counts are tightly regulated and respond to erythrocyte mass and oxygen tension. Since the discovery of erythropoietin, the erythropoietic responses to environment and tissue oxygen tension have been investigated in mice and human. Moreover,...

Thermal perturbation of mantle phase relations in subduction zones gives rise to significant buoyancy anomalies. Finite element modeling of stresses arising from these anomalies reveals transition from principal tension to compression near ∼400 km depth, down-dip compression over ∼400-690 km (peaking at ∼550 km), and transition to rapidly fading tension below ∼690 km. Such features, even when c...

To determine the role of surface tension-driven melt migration in planetary bodies, we investigated the effect of static annealing on the evolution of melt-rich bands in partially molten samples. In shear deformation experiments, deviatoric stress causes melt to segregate; when the stress is removed, surface tension causes the melt to relax back to a homogeneous distribution. Samples composed o...

part of the study " Autonomic activation and pain " , investigating responses to low-grade stress in patients with migraine, tension-type headache, fibromyalgia and chronic shoulder/neck pains. (" Samarbeidsorganet "). I wish to express my sincere gratitude to a number of people who I have had the pleasure to work with over the last years: first of all I wish to thank my supervisors Trond Sand ...

BACKGROUND The purpose of this study was to investigate the temporal relationship between autonomic changes and pain activation in migraine and tension-type headache induced by stress in a model relevant for everyday office-work. METHODS We measured pain, blood pressure (BP), heart rate (HR) and skin blood flow (BF) during and after controlled low-grade cognitive stress in 22 migraineurs duri...

The mechanism by which mechanical forces acting through skeletal muscle cells generate intracellular signaling, known as mechanotransduction, and the details of how gene expression and cell size are regulated by this signaling are poorly understood. Mitogen-activated protein kinases (MAPKs) are known to be involved in mechanically induced signaling in various cell types, including skeletal musc...

Previous work suggests that titin-based passive tension is a factor in the Frank-Starling mechanism of the heart, by increasing length-dependent activation (LDA) through an increase in calcium sensitivity at long sarcomere length. We tested this hypothesis in a mouse model (N2B KO model) in which titin-based passive tension is elevated as a result of the excision of the N2B element, one of card...

Cyclic stress strain curves (CSSC) response of Al-2024 Annealed condition was conducted under symmetric tension-compression at room temperature and constant frequency, using a servo-hydraulic testing machine, to study the effect of cooling rate on cyclic stress strain curves (CSSC) response. The fatigue response of Al-2024 alloy was evaluated macroscopically in terms of cyclic stress strain res...

The incorporation of monolayers of cultured hepatocytes into an extracorporeal perfusion system has become a promising approach for the development of a temporary bioartificial liver (BAL) support system. In this paper we present a numerical investigation of the oxygen tension, shear stress, and pressure drop in a bioreactor for a BAL composed of plasma-perfused chambers containing monolayers o...