نتایج جستجو برای: tenofovir

تعداد نتایج: 4096  

Journal: :Brazilian Journal of Pharmaceutical Sciences 2022

The objective of this study is to validate the specific questionnaire for Hepatitis B HBQOL (Hepatitis Quality Life Instrument, version 1.0) Brazilian version, in addition testing its applicability patients with hepatitis under treatment and comparing quality life between using first-line drugs (tenofovir entecavir). For validation, back-translation technique was used a sample 47 patients. Fact...

Journal: :Indian pediatrics 2015
Jagdish Kathwate Ira Shah

We describe our experience with tenofovir-based antiretroviral therapy in seven HIV-infected children after failure of first line antiretroviral drugs, or due to adverse effects to other antiretrovirals. For follow-up period of average 3.4 years, none had adverse effects or failure of treatment, indicating that tenofovir has good renal and gastrointestinal safety profile in HIV-infected Indian ...

2016
Anna Bonjoch Jordi Puig Nuria Pérez-Alvarez Javier Juega Patricia Echeverría Bonaventura Clotet Ramón Romero J. Bonet E. Negredo

Kidney injury (defined as the presence of albuminuria, proteinuria, glycosuria [without hyperglycemia], hematuria, and/or renal hypophosphatemia) is an emerging problem in human immunodeficiency virus (HIV)-infected patients, although few data are available on the role of protease inhibitors (PIs) in this condition.To determine the time to kidney injury in a cohort of HIV-infected patients rece...

2013
Kate Shearer Matthew P. Fox Mhairi Maskew Rebecca Berhanu Lawrence Long Ian Sanne

INTRODUCTION Recent WHO guidelines for resource-limited settings recommend tenofovir in first-line antiretroviral therapy (ART) yet there are suggestions that patients receiving nevirapine with tenofovir have worse outcomes than those receiving efavirenz. We sought to compare outcomes among those taking nevirapine vs. efavirenz with tenofovir and lamivudine. METHODS We analyzed data on ART na...

Journal: :The Medical journal of Malaysia 2016
H M Koh K Suresh

BACKGROUND Tenofovir (TDF) has been associated with renal function deterioration, but local data regarding the incidence and risk factors for this adverse event were lacking. OBJECTIVES To determine the incidence of nephrotoxicity in HIV-infected patients on tenofovir-based regimens and to evaluate risk factors involved in tenofovir-associated renal function decline. METHODS This is a singl...

Journal: :The Journal of antimicrobial chemotherapy 2008
José A Mira Luis F López-Cortés Pablo Barreiro Cristina Tural Manuel Torres-Tortosa Ignacio de Los Santos Gil Patricia Martín-Rico María J Ríos-Villegas José Juan Hernández-Burruezo Dolores Merino Miguel Angel López-Ruz Antonio Rivero Leopoldo Muñoz Mercedes González-Serrano Antonio Collado Juan Macías Pompeyo Viciana Vincent Soriano Juan A Pineda

OBJECTIVES To compare the response to hepatitis C virus (HCV) therapy among human immunodeficiency virus (HIV)/HCV co-infected patients receiving a nucleos(t)ide reverse transcriptase inhibitor [N(t)RTI] backbone consisting of abacavir plus lamivudine with that observed in subjects who receive tenofovir plus lamivudine or emtricitabine. METHODS A total of 256 subjects, enrolled in a cohort of...

2016
Zahari Krastev Diana Petrova Iskren Kotzev Mustafa Kemal Celen Meryl Mendelson Richa Chandra Priti Pandey Kamal Hamed

AIM To make efficacy and safety comparison of telbivudine-raodmap and tenofovir-roadmap in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) patients. METHODS This was the first prospective, randomised, two-arm, open-label, non-inferiority study in HBeAg-negative CHB patients that compared telbivudine and tenofovir administered as per roadmap concept. Patients were treated up t...

2017
David A Wohl Rima Kulkarni Will Garner Kirsten White Danielle Porter

State University, Columbus, Ohio, Capital Medical Associates, Washington DC, DC, The Dr James J Rahal Jr. Division of Infectious Disease, NewYork-Presbyterian Queens, Flushing, New York, La Playa Medical Group, San Diego, California, AIDS Healthcare Foundation, Los Angeles, California, APEX Research, Denver, Colorado, Atlanta Infectious Disease Group PC, Atlanta, Georgia, Gilead Sciences, Foste...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003
Melissa D Murphy Mary O'Hearn Sunwen Chou

We describe a 49-year-old man with human immunodeficiency virus infection and stable chronic renal insufficiency who developed acute oliguric renal failure and severe lactic acidosis and who died several weeks after tenofovir was added to an antiretroviral regimen that included didanosine. Although the role of tenofovir in precipitating acute renal failure is unclear, progressive accumulation o...

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