INTRODUCTION Tooth bleaching is based on hydrogen peroxide application. The Objective of this study was to determine whether dental bleaching agents affect metalloproteinases-mediated dentin collagen degradation. METHODS Human dentin specimens were subjected to different treatments: (1) untreated dentin; (2) demineralization by 37% phosphoric acid (PA); (3) demineralization by 37% PA, followe...

Local anaesthesia, surgery, tracheocutaneous fistula. Abstract Tracheocutaneous fistula (TCF) is a known complication of tracheostomy. It can cause problems such as saliva leak, predispose to infection from external skin into respiratory tract and cosmetically not acceptable. Treatment of the underlying infection is paramount important. Persistence of tract after sufficient duration of observat...

Aim: This randomizes clinical trial evaluated of color change, rebound effect and tooth sensitivity associated with power and at-home bleaching techniques. Methods and Materials: Anterior teeth of twenty volunteers were randomized into two balanced groups (n=20) ; Power and at-home bleaching. Color was recorded before bleaching ,immediately after bleaching, at two weeks, one, three and six mont...

Coral reefs are one of the world's most threatened ecosystems, with global and local stressors contributing to their decline. Excessive sea-surface temperatures (SSTs) can cause coral bleaching, resulting in coral death and decreases in coral cover. A SST threshold of 1 °C over the climatological maximum is widely used to predict coral bleaching. In this study, we refined thermal indices predic...

The aim of this study was to determine attitudes of final-year dental students in Cardiff, Cork and Malmö towards tooth whitening. Following receipt of ethical approval, pre-piloted questionnaires were distributed to final-year dental students in Cork, Cardiff, and Malmö as close as possible to graduation. The questionnaire sought information relating to various opinions and attitudes towards t...

OBJECTIVE Numerous studies investigated the impact of bleaching procedures on enamel microhardness. The outcomes of these studies reveal inconsistencies regarding the fact whether a microhardness reduction due to bleaching occurs or not. Aim of the present review was to summarize the existing literature of external bleaching therapies, which used microhardness tests for evaluation of possible e...

AIM This study evaluated the effect of adding calcium or fluoride to 35% hydrogen peroxide (HP) bleaching gel and the effect of human saliva on the microhardness of sound and demineralized enamel, using an in situ model. MATERIALS AND METHODS Cylindrical bovine enamel specimens (3 × 2 mm) were divided into two groups (n = 30): sound enamel (SE) and demineralized enamel (DE). Each group was di...

Burkitt lymphoma is a germinal center B-cell-derived cancer that was instrumental in the identification of MYC as an important human oncogene more than three decades ago. Recently, new genomics technologies have uncovered several additional oncogenic mechanisms that cooperate with MYC to create this highly aggressive cancer. The transcription factor TCF-3 is central to Burkitt lymphoma pathogen...

Dysregulation of canonical Wnt signaling is thought to play a role in colon carcinogenesis. β-Catenin, a key mediator of the pathway, is stabilized upon Wnt activation and accumulates in the nucleus, where it can interact with the transcription factor T cell factor (TCF) to transactivate gene expression. Normal colonic epithelia express a truncated TCF-1 form, called dnTCF-1, that lacks the cri...

Aberrant activation of β-catenin/TCF signaling is related to the invasiveness of pancreatic cancer. In the present study, we evaluated the effect of capsaicin on β-catenin/TCF signaling. In a concentration and time-dependent study, we observed that capsaicin treatment inhibits the activation of dishevelled (Dsh) protein DvI-1 in L3.6PL, PanC-1 and MiaPaCa-2 pancreatic cancer cells. Capsaicin tr...