(over 1 •~ 10-4M). These results suggest that methoxamine possesses a direct negative inotropic action which is mainly due to a decrease in the intensity of the active state. An increase in F produced by isoproterenol was antagonized by methoxamine at a concentration about 100 times higher than that of isoproterenol, suggesting a weak beta-adrenergic blocking action of methoxamine. This antagon...

A system of soft ellipsoid molecules confined between two planar walls is studied using classical density-functional theory. Both the isotropic and nematic phases are considered. The excess free energy is evaluated using two different Ansätze and the intermolecular interaction is incorporated using two different direct correlation functions (DCF's). The first is a numerical DCF obtained from si...

THREE DOCETAXEL (DX) LIPID CONJUGATES: 2'-lauroyl-docetaxel (C12-DX), 2'-stearoyl-docetaxel (C18-DX), and 2'-behenoyl-docetaxel (C22-DX) were synthesized to enhance drug loading, entrapment, and retention in liquid oil-filled lipid nanoparticles (NPs). The three conjugates showed ten-fold higher solubility in the liquid oil phase Miglyol 808 than DX. To further increase the drug entrapment effi...

Scientific publications carry a practical moral duty: they must last. Along that line of thinking, some methods are proposed to allow economically and structurally viable publication of DNA sequence data of any size in printed matter and PDFs. The proposal is primarily aimed at contributing for preserving information for the future, while allowing authors to avoid information splitting and comp...

Purpose Computing the duration of real estate assets is a challenging task due to the particularities of the property market. This paper aims to develop an empirical model to compute the interest-rate sensitivity of direct real estate assets in the Swiss multifamily housing market. Design/methodology/approach An aggregated total return index is used to empirically estimate the interest-rate sen...

The contiguous sequences of the terms (N-grams) in the documents are symmetrically distributed among different classes. The symmetrical distribution of the N-Grams raises uncertainty in the belongings of the N-Grams towards the class. In this paper, we focused on the selection of most discriminating N-Grams by reducing the effects of symmetrical distribution. In this context, a new text feature...

Until now, there has been no standard method for domain names to use characters outside the ASCII repertoire. This document defines internationalized domain names (IDNs) and a mechanism called IDNA for handling them in a standard fashion. IDNs use characters drawn from a large repertoire (Unicode), but IDNA allows the non-ASCII characters to be represented using only the ASCII characters alread...

Based on some empirical observations, we present a fairly accurate assumption about the throughput performance under non-saturation conditions and when the system is near saturation. This allows us to find a closed form solution for the transmission probabilities and collision probabilities. These can be inserted into performance expressions derived from any available analytical model for 802.1...