A series of five tetracyclic mono azo dyes based on the diazotization 1-amino-8-hydroxynaphthalene-3,6-disulphonic acid and subsequent coupling with substituted (un)sulphonated naphthalene derivatives have been synthesized. The chemical structures were established using UV–visible, IR, NMR as well mass spectrometry. Based number sulphonic other hydrophilic groups they contain, compounds showed ...

Protein-ligand complexes are often consulted for the understanding of binding modes and mechanisms of action as well as the development of novel drugs. Unfortunately the resolution of most x-ray structures is too low to resolve hydrogen atoms. However, hydrogen positions play a major role in the analysis of important interaction types as hydrogen bonding or metal interactions. Therefore, it is ...

Abstract A series of novel substituted-azo dyes 8-(aryldiazenyl)quinolin-5-ol (5a-i) were synthesized by the coupling reaction 5-hydroxyquinoline with diazotized aniline derivatives in presence NaNO2 HCl/H2O mixture. The study spectroscopic and solvatochromic properties performed FT-IR, 1H 13C-NMR UV-Visible spectroscopies. tautomerism these was studied using deuteration technique measurements....