Rising cases of antibiotic-resistant bacteria is a public health concern. Many approved antibiotics target penicillin-binding proteins example peptidoglycan transpeptidase (PTPase). Due to wide pharmacological activity of phenothiazines, new styryl, aryl, alkynyl, and thiophenyl benzo[a]phenothiazines were synthesized and their inhibitory potency against PTPasein silico and Gram-po...

This paper focuses on a coordinated tracking planning method of multiple unmanned aerial vehicles (UAVs), which was deployed in the best positions to better fulfill marine target localization tasks when approaching target. The optimal multi-UAVs implemented using an online centralized nonlinear model predictive control (NMPC) based state’s uncertainty criteria. penalty function is used solve UA...

Adequacy of a structural fire design can in theory be demonstrated through probabilistic risk assessment (PRA) where the compliance with tolerability limits and ALARP requirement are explicitly ascertained. However, explicit is challenging impractical for day-to-day designs, due to burden estimating uncertain future costs current safety investment costs. For normal conditions, use target reliab...