INTRODUCTION Pulse transit time (PTT) is the time that a pulse wave takes to travel between two different arterial points, and may be useful in estimating blood pressure. This noninvasive technique, which does not add any cost to the procedure, offers the advantage of avoiding 'arousals' during sleep measurement as occurs with ambulatory blood pressure monitoring (ABPM). We aim to confirm the u...

Objective Cuff algometry is useful to assess pain sensitivity mechanisms, but effects of cuff position and stimulation pattern are not clear. Methods In 20 healthy volunteers, cuff pain detection threshold (PDT) and pain tolerance (PTT) were recorded with cuffs accommodating two individual chambers at four locations (eight positions) along the leg, using ramp inflation (1 kPa/s) until subject...

This paper presents the Geographic Information System of the PTT Serbia, ZLWK WKH VSHFLDO DFFHQW RQ LWV XVH LQ WKH WHOHFRPPXQLFDWLRQ QHWZRUN PDLQWHQDQFH DQG OLQH IDXOWV ORFDWLQJ DQG UHSDLULQJ The system accomplishes all user needs for management, planning and the maintenance of all telephone networks. It is based on the latest scientific achievements in the area of information technologies. The...

Blood pressure is a significant vital sign; blood pressure monitoring has a great significance to determine the health status of parents. This paper proposes a continuous, non-invasive blood pressure monitoring system concept, which requires a minimum of calibrations. Using the changes in Pulse Transit Time (PTT) to derive changes in blood pressure is a new method to detect the continuous non-i...

• The synthesis and modification methods of different types 2D nanomaterials are reviewed. Recent advances in for cancer treatment imaging systematically summarized. nanomaterial-based theranostics comprehensively outlook challenges biomedical applications discussed. Two-dimensional (2D) have drawn much attention by virtue their unique physicochemical properties numerous potential applications....

This work presents a finite volume method used to solve the relevant coupled equations for general electro-osmotic flows of viscoelastic fluids, using the upper-convected Maxwell and the simplified Phan-Thien–Tanner models. Three different implementations of the electro-osmosis physical models were carried out, which depend on the required level of approximation. In the first implementation, th...

UV-induced DNA damage gives rise to mutations and skin cancer. We have previously reported that treatment of skin cells in vitro with thymidine dinucleotide (pTT) activates p53 and increases the ability of cells to repair subsequent UV-induced DNA damage by enhancing endogenous DNA repair capacity. Here we show that topical pTT pretreatment enhances the rate of DNA photoproduct removal, decreas...

Current EGFR-targeted therapy for triple negative breast cancer (TNBC) has produced disappointing results. A rational therapeutic strategy to improve EGFR-targeted treatment for TNBC is therefore needed. In this study we evaluated the feasibility of treating TNBC using photoacoustic imaging (PAI)-guided near-infrared photothermal therapy (NIR-PTT) with anti-EGFR-conjugated gold nanorods (anti-E...

We present a novel gold bellflower (GBF) platform with multiple-branched petals, prepared by a liquid-liquid-gas triphase interface system, for photoacoustic imaging (PAI)-guided photothermal therapy (PTT). Upon near-infrared (NIR) laser irradiation, the GBFs, with strong NIR absorption, showed very strong PA response and an ultrahigh photothermal conversion efficiency (η, ∼74%) among the repor...

Combination of photothermal and photodynamic therapy (PTT/PDT) offer unique advantages over PDT alone. However, to achieve synergetic PDT/PTT effect, one generally needs two lasers with different wavelengths. Near-infrared dye IR-780 could be used as photosensitizer both for PTT and PDT, but its lipophilicity limits its practical use and in vivo efficiency. Herein, a simple multifunctional IR78...