To transfer to the laboratory, the excellent efficiency shown by enzymes in Nature, biocatalysis, had to mimic several synthetic strategies used by the living organisms. Biosynthetic pathways are examples of tandem catalysis and may be assimilated in the biocatalysis field for the use of isolated multi-enzyme systems in the homogeneous phase. The concurrent action of several enzymes that work s...

In this paper new and innovative techniques during the commissioning phase of TanDEM-X will be presented that are firstly demonstrated on a satellite platform. The focus is on the secondary goals of TanDEM-X that are assigned for the third year of the mission time life due to the tight schedule for the acquisition of the highly accurate global digital elevation model. Therefore, a variety of sc...

A 42 years old gentleman presented with predominant low back pain associated with bilateral lower limb neurological deficit leading to an initial diagnosis of lumbar stenosis. Further history taking and examination revealed upper limb neurological deficit, and the lower limbs actually presented with upper motor neuron instead of lower motor neuron signs. Imaging studies confirmed the clinical f...

BACKGROUND Clinical success with chimeric antigen receptor (CAR)- based immunotherapy for leukemia has been accompanied by the associated finding that antigen-escape variants of the disease are responsible for relapse. To target hematologic malignancies with a chimeric antigen receptor (CAR) that targets two antigens with a single vector, and thus potentially lessen the chance of leukemic escap...

BACKGROUND How tandem autologous-allogeneic stem cell transplantation should be integrated in the treatment of multiple myeloma remains controversial. We examined the long-term outcome of patients with multiple myeloma managed with tandem autologous-allogeneic stem cell transplantation and present a prognostic factor analysis based on the experience of the Société Française de Greffe de Moelle ...

ABSTRAK
 Depresi yang sering dialami oleh lanjut usia perlu mendapatkan penanganan cepat, tepat dan terstruktur dari support system ada lingkungan terdekat. Keluarga, komunitas lansia kader kesehatan di masyarakat harus memiliki kemampuan dasar untuk mengatasi stres dengan pendekatan non farmakologi. Tujuan pengabdian kepada ini adalah lansia, keluarga mampu meningkatkan pengetahuan ketram...

BACKGROUND Patients with isolated middle cerebral artery (MCA) and tandem MCA/internal carotid artery (ICA) obstruction have similar presenting symptoms and stroke severity. We aimed to investigate early recanalization of MCA and clinical outcomes in patients with tandem ICA/MCA obstructions and isolated MCA occlusion. METHODS Patients with MCA occlusion on pretreatment transcranial Doppler w...

Two new analogues of TANDEM (des-N-tetramethyl triostin A) have been synthesised in an effort to elucidate the molecular basis of DNA nucleotide sequence recognition in this series of compounds. Their binding preferences have been investigated by DNAase I footprinting and differential inhibition of restriction nuclease attack. The presence of a single N-methyl group on only one valine residue (...

Radar interferometry is a technique which makes use of interfered signal of two radar echoes for topographic elevation and terrain element mapping. ERS Synthetic Aperture Radar (SAR) tandem pair with minimum possible temporal baseline of 1-day and with precise orbit control to obtain suitable interferometric spatial baseline is appropriate for interferometric study in terrain analysis. In this ...