INTRODUCTION Adults with intellectual disabilities (ID) have significantly lower rates of physical activity and fitness than adults without ID. The 6-min walk test (6 MWT) is an inexpensive and simple way to test mobility and submaximal work capacity. PURPOSE To evaluate the test-retest reliability and validity of the 6 MWT in adults and seniors with ID and explore factors contributing to the...

Three hundred and four patients with clinically proven, non-toxic diffuse goitre were investigated. Iodine uptake was performed according to a standard technique, i.e., 2 hour, 24 and 48 hours after oral administration of Radio Iodine. Serum thyroid hormones (T4 T3, FF4, and T3-uptake) and TSH were measured by RLA techniques and results were compared with normal Two types of kits were used, the...

It is known that thyroid hormone enhances the biosynthesis of phosphatidylcholine in the lung. The purpose of the present study was to investigate the effects of thyroid hormone on the activity of cholinephosphotransferase, the terminal enzyme in the CDP-choline pathway, in guinea pig lung mitochondria and microsomes. Intramuscular injection of triiodothyronine (T3, 0.25-4 mg/kg body wt) stimul...

We investigated the mechanism by which T4 regulates its activation to T3 by the type 2 iodothyronine deiodinase (D2). D2 is a short- lived (t1/2 50 min), 31-kDa endoplasmic reticulum (ER) integral membrane selenoenzyme that generates intracellular T3. Inhibition of the ubiquitin (Ub) activating enzyme, E1, or MG132, a proteasome blocker, inhibits both the basal and substrate-induced acceleratio...

Over-accumulation of cadmium and lead in rice grain is a global concern as it has adverse health impacts. Atmospheric deposition an important source heavy metal accumulation soil, but contribution to crops not been quantified the mechanisms foliar Cd Pb uptake via stomata leaves exposed atmospheric fallout are unclear. To quantify on grains, pot experiment with four exposure treatments (T1, all...

The performance characteristics of assays is reported for thyroxine (T4), triiodothyronine (T3), and T3-uptake (T3U) using the GAMMAFLOTM Automated Assay System. A comparison of calculated free thyroxine index (FTI) values is also presented. This automated radioimmunoassay (RIA) system utilizes a combination of continuous-flow methodology and chromatographic separation techniques. The T4 assay ...

Local 5'-deiodination of serum thyroxine (T4) is the main source of triiodothyronine (T3) for the brain. Since we noted in previous studies that the cerebral cortex of neonatal rats tolerated marked reductions in serum T4 without biochemical hypothyroidism, we examined the in vivo T4 and T3 metabolism in that tissue and in the cerebellum of euthyroid and hypothyroid 2-wk-old rats. We also asses...

• PK216LH, which is a cation-exchange resin, could remove NH 4 + in an aqueous solution. The simultaneous use of Mg–Al LDO and PK216LH not sufficiently lactate . individual two stages efficient proliferation pluripotent stem cells mass cell culture hindered by the release metabolites such as ammonia. In this work, porous strong-acid cation exchange resin (PK216LH) layered doubled oxide (LDO) we...