Thyroid hormones (THs) are key regulators of metabolism. The thyroid gland produces both thyroxine (T4) and triiodothyronine (T3). T4 is the main product and is converted in the periphery via deiodination to T3 which is the main biologically active TH. The production of THs is regulated by thyrotrophin (TSH) in response to TSH releasing hormone (TRH). This, in turn, is regulated by a negative f...

Changes in plasma thyroxine (T4), triiodothyronine (T3), free thyroxine index (FT4I) and thyroid stimulating hormone were studied in 100 patients with Graves' disease treated with carbimazole. During therapy plasma T3 concentrations were disproportionately high compared to those of T4, the T4 : T3 ratio was low, and many patients were clinically euthyroid with a normal plasma T3 but low T4 conc...

The serum thyroid stimulating hormone (TSH) level is decreased in acromegalic patients. Although this phenomenon is thought to be caused by the enhanced secretion of somatostatin which suppresses TSH production, it has not yet been proven. We describe a 60-year-old woman with acromegaly who showed a low concentration of TSH. We diagnosed her as painless thyroiditis based on an increased level o...

Thyroid hormones were measured in plasma of genetically lean (LL) or fat (FL) chickens at different ages. No differences were observed at hatching or at adult age. More triiodothyronine (T3) and less thyroxine (T4) were found in the plasma of LL than in FL at the fed state during the growth period. This difference disappeared as the birds approached sexual maturity. Dietary supplementation by T...

Thyroid hormones affect in vitro metabolic intensity, increase basal metabolic rate (BMR) in the lab, and are sometimes correlated with basal and/or resting metabolic rate (RMR) in a field environment. Given the difficulty of measuring metabolic rate in the field-and the likelihood that capture and long-term restraint necessary to measure metabolic rate in the field jeopardizes other measuremen...

OBJECTIVE Deposits of myxoid material, similar to myxedema related to thyroid disease, are described in the medial layer of aortas with dissection. We analyzed the clinical or subclinical thyroid dysfunction of patients with this disease and analyzed whether a correlation exists between serum levels of thyroid-related hormones and the myxoid content of the aortic media. METHODS We measured, w...

The protective effects of red cabbage and garlic extracts against liver, kidney thyroid gland damage induced by fumonisin B1 (FB1) in male mice were studied. Sixty divided to six groups. Group one are the healthy mice, two that received a daily oral dose only FB-1 (100 µg/kg.b.w) for 1 month, three: extract (500 mg/kg.bw) plus FB1, four: extracts, five: (500mg/kg.bw) group 6:are extract. After ...

This study was aimed to investigate the effects of L-carnitine (Car), creatine monohydrate (CrM) and their combination (CarCrM) as dietary antioxidants materials on productive performance, digestibility, ileal eubiosis, blood chemistry redox system stressed quails challenged by lead acetate (LA) in drinking water. In total, 600 were assigned into 5 treatments with 4 replications each 30 chicks ...

Hypothyroidism may reduce, whereas hyperthyroidism may aggravate, asthma symptoms. The mechanisms underlying this relationship are largely unknown. Since thyroid hormones have central roles in cell growth and differentiation, we hypothesized that airway remodeling, in particular increased airway smooth muscle (ASM) mass, may be involved. To address this hypothesis, we investigated the effects o...