Background: Rheumatoid Arthritis patients are evaluated during treatment for various inflammatory factors such as C-reactive protein, Erythrocyte Sedimentation Rate, and Disease Activity Score, and other immune system-related factors. In the follow-up of patients with rheumatoid arthritis, hematologic factors associated with the immune system especially Platelet to Lymphocyte Ratio and Neutroph...

INTRODUCTION Antimicrobials are widely used in infectious diseases. Only the timely intervention will contribute to the positive outcome of the disease. Unjustified use of antimicrobial prophylaxis may have adverse effects, i.e., result in bacterial resistance to existing antimicrobials, as well as toxic effects on leukocyte lineage and other parameters of the blood. GOAL The goal of this stu...

Introduction: Leukocytes causing a wide variety of side effects after transfusion are present in all blood products prepared by standard methods. As a consequence, the use of filter technology for leukoreduction has been widely practiced .According to AABB accreditation in 1996, leukoreduced blood components must contain less than 5×106 leukocytes per unit, but sometimes this value is higher ev...

Platelet counting in patients with acute leukemia or disseminated intravascular coagulation (DIC) may have a risk for erroneous counts owing to the presence of nonplatelet particles or platelet activation. We evaluated automated platelet counting methods using the Abbott Cell-Dyn Sapphire (Abbott Diagnostics, Santa Clara, CA), Sysmex XE-2100 (Sysmex, Kobe, Japan), ADVIA 2120 (Siemens Diagnostic...

conclusions in cd4 positive cell count below 500, the dominant radiographic pattern of tuberculosis is atypical presentation. at this level of immunity, cd 4 positive t cell dysfunction may play a deterministic role in tb radiographic manifestation. results of a total 15 patients (86.7% men and 13.3% women), 78.6% had cd4 positive counts below 350 (mean ± sd; 229.15 ± 199.45). the most common r...

Abstract Background Thyroid hormones have a crucial role in metabolism and proliferation of blood cells. Thyroid dysfunction induces different effects on blood cells such as anemia, erythrocytosis leukopenia, thrombocytopenia, and in rare cases causes’ pancytopenia. It also alter RBC indices include MCV, MCH, MCHC and RDW. Thus this study attempted to evaluate effect of hypo & hyperthyroi...

abstract background leukemia is the most prevalent childhood cancer and acute lymphoblastic leukemia (all) constitutes 75% of all cases. the most frequent presenting symptoms are fever, weight loss and pallor. early detection of clinical symptoms positively affects timely diagnosis. the objectives of the present study were to assess frequency of presenting symptoms, laboratory data, immune phen...

INTRODUCTION The investigation of platelet function by aggregometry requires specialist equipment and is labour intensive. We have developed an automated platelet aggregation method on a routine coagulation analyser. METHODS We used a CS-2000i (Sysmex) with prototype software to perform aggregation in platelet-rich plasma (PRP), using the following agonists: ADP (0.5-10 μm), epinephrine (0.5-...

Young (immature) platelets containing residual RNA, so-called reticulated thrombocytes, appear in the peripheral blood after the release from bone marrow. It has been shown that the count of the reticulated platelet correlates with the megakaryocyte mass. As of late, the immature platelet fraction (IPF) may be reliably quantified with the fully automated blood analyzer Sysmex XE-2100. IPF may b...

Diagnosis of urinary tract infection (UTI) is primarily done by microbiologic culture, which is time-consuming and can produce false-positives and false-negatives. Flow cytometry allows for rapid screening of many samples and eliminates culturing. We analyzed the Sysmex UF-1000i (TOA Medical Electronics, Kobe, Japan) for accuracy in identifying RBCs and WBCs, casts, bacteria, and epithelia. We ...