INTRODUCTION: Acceptable maxillary growth in bilateral cleft lip and palate (BCLP) is difficult to achieve. Pre-surgical orthopedic treatment aims at the reduction of size by guiding functional rehabilitation. The objective this study was evaluate impact Orthopedics Appliances (PSOAs) on facial BCLP. MATERIALS AND METHODS: Consented subjects were patients who treated Hospital Universiti Sains, ...

A fissura de lábio e ou palato não sindrômicas são anomalias congênitas craniofaciais mais frequentes. Elas ocasionam problemas estéticos funcionais que requerem tratamento em longo prazo, envolvendo reabilitação multidisciplinar incluindo a fonoaudiologia fisioterapia. Este estudo propõem apresentar alguns dos princípios atuação do fonoaudiólogo fisioterapeuta nas fissuras orofaciais sindrômic...

It is suspected that environmental exposure to non-syndromic oral clefts, which includes cleft lip (CL), and palate (CLP) has an effect on epigenetic mechanisms, particularly deoxyribonucleic acid (DNA) methylation. DNA methylation will be expressed during facial morphogenesis have impact development. This study aimed observe differences in between CL CLP, mothers CLP mothers, correlation mothe...

Dear Editor: Increased homocysteine levels due to vitamin B6 or B12 deficiency or genetic defects in folate pathway genes are associated with an increased incidence of non-syndromic cleft lip with or without cleft palate (NSCLP) [1] . Thymidylate synthase (TS) is a folatedependent enzyme that catalyzes methylation of 29-deoxyuridine-59-monophosphate (dUMP) to 29-deoxythymidine-59-monophosphate ...