Two hundred and fifty one cases of penetrating wounds of the chest were studied prospectively. Clinical evidence is presented to show that: basal intercostal drains are adequate to remove both air and fluid from within the pleural cavity; frequent chest radiographs are unnecessary and intercostal drains may be removed on clinical grounds alone; long term antibiotic prophylaxis is unnecessary; e...

A white female child weighing 3.4 kg at birth after a forceps delivery was found to have bilateral congenital dislocation of the hip, which was successfully treated conservatively without anaesthesia, but was otherwise normal on clinical examination. When 7 months old, she presented with a 3-month history of symptomless tumours of the scalp, face, upper back and groin, and biopsy revealed lymph...

Chagas disease, caused by the protozoan Trypanosoma cruzi, has a variable clinical course, ranging from symptomless infection to severe chronic disease with cardiovascular or gastrointestinal involvement or, occasionally, overwhelming acute episodes. The factors influencing this clinical variability have not been elucidated, but it is likely that the genetic variability of both the host and the...

The thyroid gland is an endocrine organ that secretes the hormones triiodothyronine (T3) and thyroxine (T4), which are, in turn, under the influence of the TSH and the TRH. Though hyperand hypothyroidism remain the common clinically manifesting condition of the thyroid, in some cases, the patient remains symptomless with either excess or decrease in thyroxine levels, along with normal TSH level...

The thyroid gland is an endocrine organ that secretes the hormones triiodothyronine (T3) and thyroxine (T4), which are, in turn, under the influence of the TSH and the TRH. Though hyperand hypothyroidism remain the common clinically manifesting condition of the thyroid, in some cases, the patient remains symptomless with either excess or decrease in thyroxine levels, along with normal TSH level...

Phonocardiography is of great importance in distinguishing coronary artery fistula from other anomalies with a continuous murmur. The presence of this murmur at the apex must be regarded as an important characteristic of a coronary artery fistu!a, especially when the maximum diastolic murmur is found at the apex. Although coronary artery fistula may be symptomless for a long time, surgical trea...

We report the case of a 48-year-old woman who developed morphea-like plaques after 1 year of treatment with D-penicillamine at 250 mg daily for a seronegative erosive arthritis of rheumatoid type. The rash began as several red itchy patches on the trunk; these became thickened and shiny over about 3 months. The histological appearance was of increased dermal fibrosis with an inflammatory infilt...

We report the case of a 58-year-old patient, with a three vessel disease with unstable angina. Due to refractory angina, she was referred to urgent coronary artery bypass graft (CABG). In the preoperative evaluation were found severe obstructive lesions in the brachiocephalic trunk origin, left common carotid origin and left internal carotid artery. The patient underwent CABG, supra-aortic trun...

this study determines the value of linkage analysis using six rflp markers for carrier detection and prenatal diagnosis in familial dmd/bmd cases and their family members for the first time in the iranian population. we studied the dystrophin gene in 33 unrelated patients with clinical diagnosis of dmd or bmd. subsequently, we determined the rate of heterozygosity for six intragenic rflp marker...