BACKGROUND Myrtus communis has been suggested as a sleep aid in unconventional medicine. Moreover, previous studies have also indicated its sedative- and hypnotic-like activity. In this study, the hypnotic effect of M. communis was investigated. METHODS Essential oil (EO) of M. communis (600, 800, and 1,000 mg/kg) was given orally to Swiss albino mice of both sex, and the hypnotic effect was ...

The aim of this study was to evaluate antitumour activity of the roots of Hibiscus tiliaceus Linn. against Dalton’s Ascitic Lymphoma (DAL) in Swiss albino mice. A significant enhancement of mean survival time (MST) of H. tiliaceus treated tumour bearing mice was found with respect to control group. H. tiliaceus treatment was found to enhance peritoneal cell counts. When these H. ti...

The in vivo protective role of hydro-methanolic root extract of Withania somnifera (WS) was evaluated in alleviating lead nitrate (LN)-induced toxicity in male Swiss albino mice by measuring hematoserological profiles. The lead-treated (20 mg/kg body wt, p.o.) albino mice (25-30 g) concurrently received the root extract (200 and 500 mg/kg body wt, p.o.) once daily for the duration of six weeks....

The current study aims at determining the antioxidant properties of Morus alba leaves extract (MLE) on various organs of mice. Forty male Swiss albino mice were divided into control group and three different groups which received three different doses of MLE orally for 10 days. The glutathione, nitrite/nitrate, malondialdehyde levels were estimated in kidney, testis, spleen and jejunum of adult...

The histochemical effects of the lipid and the biochemical analysis of cholesterol content induced by mancozeb, a widely used fungicide in India and in Madhya Pradesh were observed on Swiss albino mice (Mus musculus albinicus). Three groups were used for the present experiment, where Group I was taken as control and was administered distilled water. Group II and III were the test groups receivi...

AIM To use the tyrosinase minigene as a visual marker to perform microinjection training and improve the techniques related with transgene to greatly elevate the efficiency of gene transfer. METHODS A mouse tyrosinase minigene, i.e., TyBS, in which the 2.25-kb authentic genomic 5' non-coding flanking sequence of mouse tyrosinase was fused to a mouse tyrosinase cDNA, was introduced into the fe...