Recipient Swiss albino mice which received sensitized cells from peritoneal exudates (PEC), thymus (T) and bone marrow(BM) were exposed to lead and challenged with human dwarf tapeworm Hymenolepis nana. Oral lead exposure suppressed the immune response as indicatd by low values of different fractions of immunoglobulins and increase in susceptibility to infection at larval and adult developmenta...

The spreading of viral RNA within Swiss Albino mice orally inoculated with coxsackievirus B4 E2 strain (CVB4 E2) was studied by using RT-PCR and semi-nested-RT-PCR methods. Viral RNA was detected in various organs: pancreas, heart, small intestine, spleen, thymus, and blood at various postinfectious (p.i.) times ranging from 8 hr to 150 days. Our results show that (i) outbred mice can be infect...

Berberis asiatica Roxb. Ex. Dc., non Griff. Belongs to the family berberidaceae commonly occurring in the dry outer Himalaya, Assam etc. Roots along with stem bark s a reputed drug in Ayurvedic medicine contain several alkaloids. 50% Ethaolnic extract of roots reported to posses anti-cancer activity. The present study examines the antitumour effect of ethanolic root extract (BRE) against Dalton...

Prunus domestica fruits extract (PDE) was evaluated for in vivo radioprotective activity against whole body gamma irradiation in Swiss albino mice. The irradiation of mice resulted in significant elevation of lipid peroxidation in terms of thiobarbituric acid reactive substance (TBARS) and depletion in glutathione (GSH), protein, superoxide dismutase (SOD) and catalase at all the intervals stud...

The influence of previous sexual experience and subsequent differential housing on the epididymis and fertility index was studied for male Swiss albino cc mice. Among animals with previous sexual experience those having a high epididymal beta-glucuronidase activity showed a high fertility index and vice versa. The reproductive potential of animals without previous sexual experience was reduced ...

OBJECTIVE Benzophenone semicarbazone (BSC) was synthesized and characterized to identify compounds with anticancer activities. METHODS Anticancer activities were studied against Ehrlich Ascites Carcinoma (EAC) cells in Swiss albino mice by monitoring parameters such as tumor weight measurement, survival time of tumor bearing mice, tumor cell growth inhibition, and so on. Some hematological pa...

Background: This study has been undertaken to find out the possible radioprotective potential of the Alstonia scholaris extract (ASE). Materials and Methods: For experimental study, healthy Swiss albino male mice were selected from an inbred colony and divided in four groups. Group I (normal) did not receive any treatment. Group II was orally supplemented ASE once daily at the dose of ...

      Genistein is a soya isoflavone, which is found naturally in legumes, such as soybeans and chickpeas. The intraperitoneal administration of the optimum dose (200 mg/kg) of genistein 24 h and 15 minbefore irradiation (8 Gy at a dose rate of 1.02 Gy/min) recovered the deficit in protein content (28.63±1.44%) and the DNA content (21.61±8.19%) if an average of 5 intervals of autopsies 1st...