A near-complete sequence of the human genome is now available, and many efforts are currently focused on the next logical biomedically relevant target — the mouse genome. Given limited resources, which vertebrate genome(s) should be tackled after that? Reasonable candidates include other well-studied model organisms such as Rattus rattus (the rat), Xenopus laevis (the African clawed toad), and ...

Gap junction channels are formed by members of the connexin gene family and mediate direct intercellular communication through linked hemichannels (connexons) from each oftwo adjacent cells. While for most connexins, the hemichannels appear to require an apposing hemichannel to open, macroscopic currents obtained fromXenopus oocytes expressing rat Cx46 suggested that some hemichannels can be re...

We read with profound interest the article titled ‘Increased hypoxic dose after training at low altitude with 9h per night at 3000m normobaric hypoxia’ by Carr et al. (2015). Authors have concluded that low altitude (1380 m) combined with normobaric hypoxia of 3000 m improves total haemoglobin mass (Hbmass) and is an effective alternate method for training. Like other studies on elite athletes,...

We present results for VCSEL based links operating PAM-4 signaling using a commercial 0.13μm CMOS technology. We perform a complete link analysis of the Bit Error Rate, Q factor, random and deterministic jitter by measuring waterfall curves versus margins in time and amplitude. We demonstrate that VCSEL based PAM–4 can match or even improve performance over binary signaling under conditions of ...

Thermal expansivity (α, 1–300 K), heat capacity (CP, 1–108 K), electrical conductivity (σ, 1–300 K) and magnetic susceptibility (χ, 1–300 K) data have been obtained for a Bridgman-grown single grain iAl68.9Pd21.6Mn9.5 quasicrystal (BR) for direct comparison with data previously published for a flux-grown single grain sample [ Phys. Rev. B 65 184206 (2002)], and present σ, χ and CP data for a se...

We are excited to introduce the special issue of Israel Journal Chemistry dedicated awarding Wolf Prize in 2022 Benjamin Cravatt for his “contributions understanding chemistry cellular communication and inventing chemical methodologies study role carbohydrates, lipids, proteins such biological processes”. To celebrate Ben's countless achievements, we have invited several previous trainees, coll...

Sensitive immunoradiometric (IRMA) and ELISA Supplementary key words sandwich blotting immunoblotting assays for cholesteryl ester transfer protein (CETP) have been native gel electrophoresis prebeta migrating Superose Superdex developed using two different monoclonal antibodies (MAbs). HepG2 cells The MAbs were prepared against human plasma CETP and demonstrated specificity by their inhibition...

Adaptive Case Management deals with processes that are not predefined or repeatable, but depend on evolving circumstances and decisions regarding a particular situation. While case management is often considered as different from conventional business process management, in reality they cannot be strictly separated. A structured business process can contain parts which deal with non-routine cas...

Much research has focused on youth who are rejected by peers; who engage in negative behavior, including aggression; and who are at risk for adjustment problems. Recently, researchers have become increasingly interested in high-status youth. A distinction is made between two groups of high-status youth: those who are genuinely well liked by their peers and engage in predominantly prosocial beha...

This project attempts to gain a better understanding of anxiety and reviews information regarding anxiety. It reviews Adlerian approaches for treating anxiety, and a review of recently published Adlerian research regarding anxiety is presented. This paper proposes that music is a creative tool that can be used as a component in some Adlerian psychotherapeutic and counseling processes for treati...