The aim of this study was to design and optimize risperidone (RIS) mucoadhesive buccal tablets for systemic delivery as an alternative route. Direct compression method was used for the preparation of buccal tablets, and screening studies were conducted with different polymers to determine their effects on tablet characteristics. Carbopol® (CP) and sodium alginate (SA) were selected as two polym...

fresh semen obtained from infertile men occasionally exhibits the total absence of motile sperm (100%asthenozoospermia). vitality tests may reveal that a proportion of the immotile sperm has functional membranes, which are considered viable. an easy test for the prior determination of sperm viability may assist in sperm selection for the microinjection of oocytes. the main objective of this stu...

the objective of the present study is to develop and investigate the swelling behavior of ph-sensitive superporous hydrogel (sph) and sph composite (sphc). a novel superporous hydrogel containing poly (methacrylic acid-co-acrylamide) was synthesized from methacrylic acid and acrylamide through the aqueous solution polymerization, using n,n-methylenebisacrylamide as a crosslinker and ammonium pe...

semen analysis, sperm dna fragmentation (sdf) and hypo-osmotic swelling test (host) are usually performed for the evaluation of sperm fertilizing ability. there are some debates over the necessity of sdf and host incorporation in male infertility work-up.semen of 77 men was evaluated by sdf and host through three semen analyses. sperm parameters were arranged into different categories: < 5%, 5-...

Gas injection into heavy oil reservoirs could result in high ultimate recovery of oil. Experimental studies showed that an application of a combined technology of Gas Assisted Gravity Drainage (GAGD) and Vapor Extraction (VAPEX) could increase final oil recovery of a candidate viscous oil reservoir. In this paper the results of laboratory investigation are presented, including Pressure-Volu...

background: recurrent abortion is defined as three or more consecutive pregnancy losses. we aimed to determine the relationship between male sperm parameters and hypo-osmotic swelling score and recurrent abortion. we also studied whether washing of spermatozoa and intrauterine insemination in patients with recurrent miscarriage and low score hypo-osmotic swelling test in male partners could imp...

pachydermodactyly is a rare and benign disease that may be idiopathic, genetic, acquired as a response to repetitive trauma, or associated with several other acquired conditions often pushing the health caregiver to do a bunch of costly lab tests and diagnostic workups to rule out other entities. all health care givers must be aware about this disease for reassure the patients and cut unnecessa...

introduction: acute pain and swelling following endodontic treatment are challenges for patients and dentists. according to previous studies, the incidence of flare-ups increases after endodontic treatment of teeth with necrotic pulp. calcium hydroxide is currently used as a multipotential medicament in root canal therapy. the aim of this study was to evaluate the incidence and severity of flar...