In this study, porous natural rubber (NR) films loaded with silver nanoparticles (AgNPs) were prepared by the solvent casting method. The structure of NR was formed hydrophilic substances such as glycerol, pectin or carrageenan. film properties including morphology, mechanical test, hydrophilicity evaluation, water absorption, release and antibacterial activity determined. From results, morphol...

Abstract: Objectives: Stavudine has a low half-life of 0.8-1.5 hr and therefore needs recurrent administration to sustain stable beneficial drug plasma levels. In order enhance preserve the level stavudine for round clock, gastroretentive systems (floating low-density formulations that cause buoyancy on gastric fluid in stomach) may prove be advantageous releasing content from matrix tablet res...

Opipramol 2-HCl (OP) is used for therapy of general somatoform and anxiety disorders. Conventional tablets in the market contain 50 mg OP to be used once or up to three times a day in effective treatment of depression in mild. In case of serious depressive disorders, OP may be administired up to 300 mg a day. Decrease in frequency of high dose administration via sustained drug release would red...

Nowadays, the standard media used in clinical-scale mesenchymal stem cell (MSC) production to supply hundreds of clinical trials uses animal-derived components as supplements, which raises several health concerns. Consequently, development xeno-free supplements has emerged. In current study, effect pulse electric field (PEF) application platelet concentrates (PC) with no therapeutic value for p...

in the present study, floating drug delivery beads (fdds) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. in order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the consti...