Temperature sensitive Pluronic (Plu) and pH-sensitive polyacrylic acid (PAA) were successfully mixed in different ratios to form in situ gelling formulations for colon cancer therapy. The major formulations were prepared as the liquid and solid suppository dosage forms. Epirubicin (Epi) was chosen as a model anticancer drug. In vitro characterization and in vivo pharmacokinetics and therapeutic...

Delirium is a significant problem in palliative medicine, and its proper management and prevention is extremely important. In our cancer center, mianserin suppositories have been included in the hospital formulary and are prescribed for cancer patients who have dysphagia; however, previous studies have shown only limited data on the effect of mianserin suppositories. Therefore, in this study, w...

We give an overview of known results on stability and instability in two problems: the Gel’fand inverse boundary value problem and the inverse scattering problem(3D). In particular, we present our new instability estimates, see [M. Isaev, Exponential instability in the Gel’fand inverse problem on the energy intervals, J. Inverse Ill-Posed Probl., Vol. 19(3), 2011, 453-473] and [M. Isaev, Expone...

?+orl the . The wise physician has never underrated importance of diet in the treatment o but at the beginning of the present ce western countries the field of dietetics, 1 ,, as it was applied to the general SUPP , , healthy population, was mamly . ? jg cranks, who were as wrong in most of and fancies and in the baseless theories Propounded as they were right m their in that more attention sho...

A double-blind cross-over study of 35 out-patients with rheumatoid arthritis showed that Naproxen and Indomethacin suppositories were both effective forms of treatment in rheumatoid arthritis, both being significantly superior to placebo in terms of relief of morning stiffness.

UNLABELLED The aim of the current research is to identify the clinical and microbiological effect of 5-nitroimidazol therapy for the treatment of bacterial vaginosis and in combination with probiotics and the influence of such therapy upon vaginal flora. MATERIALS AND METHODS Women (n = 539) with bacterial vaginosis who meet the criteria were included in the study. They were randomized into t...

In Bangladesh about nineteen different Indomethacin marketed preparations (including capsule and suppository) are available. Of them nine brands dosage forms, potency of which was assayed by UV spectrophotometry dissolution study carried out according to the USP pharmacopoeial method evaluate their quality. The result showed that eight capsules (89%) met specification remaining one brand less p...

Background: Vulvovaginal candidiasis is one of the most common infections in gynecologic filed, and non–albicans Candida species are emerging causative microorganisms. This species shows resistance to routine treatments. One of the suggested treatments is administration of vaginal suppositories of boric acid. The aim of the present study was to compare boric acid with clotrimazole in the treatm...

background: narcotic drugs are usually used for postoperative pain control which could cause several complications such as respiratory depression and apnea. therefore, replacement of these drugs with safer analgesics is recommended. the aim of this study was to compare the analgesic effects of suppository diclofenac and pethidine in post-cesarean section (c/s) patients. methods: in this clinica...