Superoxide dismutase has been identified and peroxidatic activity demonstrated in Mycobacterium leprae. The superoxide dismutase, shown indirectly to be a manganese-containing enzyme, was present at low activity in the cell-free extract. Peroxidatic activity was detected in a haemoprotein on polyacrylamide gels, but quantitative assay was not possible. Catalase, although present in a cell-free ...

This study was carried out to assess the developmental pattern of copper- and zinc-containing superoxide dismutase (CuZnSOD), manganese-containing superoxide dismutase (MnSOD), glutathione peroxidase (GSH-Px) and catalase (CAT) activity in rat brain. The enzymes studied were assayed in different brain regions (cerebral cortex, striatum, cerebellum and brainstem) and enzyme values were corrected...

Rare earth element pollution (REEs) and acid rain (AR) pollution simultaneously occur in many regions, which resulted in a new environmental issue, the combined pollution of REEs and AR. The effects of the combined pollution on the antioxidant enzyme system of plant roots have not been reported. Here, the combined effects of lanthanum ion (La3+), one type of REE, and AR on the antioxidant enzym...

OBJECTIVE The aim of the present study was to evaluate clinical effects of supplementation with antioxidants to patients with severe erythrodermic (EP) and arthropathic (PsA) forms of psoriasis. METHODS Fifty-eight patients were hospitalized, treated by conventional protocols, and randomly assigned to four groups. Groups EP1 and PsA1 were supplemented with coenzyme Q(10) (ubiquinone acetate, ...

PURPOSE To ameliorate experimental optic neuritis by combining scavenging of superoxide by germ line increases in the extracellular superoxide dismutase (ECSOD) and hydrogen peroxide by viral-mediated gene transfer of the human catalase gene. METHODS The human catalase gene inserted into recombinant adeno-associated virus (rAAV) was injected into the right eyes of transgenic mice overexpressi...

Many plants are claimed to possess antidiabetic and antioxidant activity. In practice, it is being increasingly recognized to be an alternative approach to modern medicine. This study assess the antioxidant capacity of Tinospora cordifolia stem methanol extract in daily oral administration of 500 mg/kg of body weight for 40 days in alloxan induced diabetic rats. The erythrocytes membrane lipid ...

AIM To investigate the effects of MnTE-2-PyP on some markers of antioxidant defence system in asthma mice model. MATERIAL AND METHODS The animals were divided into four groups: group 1, controls; group 2, injected with ovalbumin, group 3, treated with MnTE-2-PyP, and group 4, treated with ovalbumin and MnTE-2-PyP. The activities of superoxide dismutase, catalase, glutathione peroxidase and no...

The concepts of oxidative stress and antioxidants have been implicated in neurodegenerative disorders. Oxidative stress was assessed by estimating lipid peroxidation product in the form of thiobarbituric acid reactive substances (TBARS). Enzymatic antioxidants like superoxide dismutase(SOD), glutathione peroxidase(GPx), catalase, ceruloplasmin and non enzymatic antioxidant vitamins like vitamin...

BACKGROUND The pathophysiology of migraine and other headaches is still unknown, and research is mostly done on neurotransmitter, biochemical and vascular mechanisms. The aim of this study was to examine the role of antioxidant enzymes in the pathophysiology of headache in the interictal period of the pain process. METHODS In this study, glutathione peroxidase, catalase and superoxide dismuta...

The two-location field experiment was conducted to study the possible alleviation of droughtstress effects on red bean by ultrasonication and 24-epi-brassinolid. Locations were AgriculturalResearch Center in Shahrood, Iran and the other in bean farm, 40 km off Shahrood city in 2015.Experiment factors included irrigation of main plots at three levels of normal irrigation (60 mmevaporation from e...