The antioxidant potential of crude methanol extract (CE) as well as chloroform (CF), ethyl acetate (EF) and n-butanol (NF) soluble fractions of Enhydra fluctuans Lour, which is widely used in indigenous system of medicine for different purposes, were studied. The antioxidant potential of extract/different fractions were evaluated using different in vitro antioxidant models. In addition, total a...

A series of Graphene Oxide/ Polyacrylamide (GO/PAM) super-elastic nanocomposites with different amounts of Graphene Oxide Nanosheets (GONSs) (0.5, 1, 1.5, and 2 wt. %) were synthesized using an in-situ polymerization in an aqueous medium in this paper. To this end, we proposed a method for obtaining super-elastic nanocomposites with a high dispersion of GONSs in the PAM chains as well as in a r...

The enzyme nitric oxide synthase is both medically relevant and of particular interest from a basic sciences perspective due to the complex nature of the chemical mechanism used to generate NO. The enzyme utilizes multiple redox-active cofactors and substrates to catalyze the five-electron oxidation of substrate l-arginine to citrulline and nitric oxide. Two flavins, a cysteine-coordinated heme...

Menadione (MD; 2-methyl-1,4-naphthoquinone), a redox cycling quinone was shown to induce single (ss)- and double (ds)-strand DNA breaks in human MCF-7 cells. This DNA damage was mediated via the hydroxyl radical as evidenced by electron spin resonance spectroscopy (ESR) studies utilizing the spin trap, 5,5-dimethyl-1-pyrroline-1-oxide. The free radical production and DNA damage were shown to pl...

Using the spin trap a-(4-pyridyl-l-oxide)-A'-fert-butylnitrone, we have detected a lipid-derived carbon-centered free radical generated from in tact 1,1210 lymphoblastic leukemia cells that were exposed to 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (edelfosine or I IIK-()( II,) and oxidative stress. The spectral characteristics, including hyperfine splitting constants of ¡IN= 15.61G...

Various nanoparticles (silicon oxide, tin oxide and aluminium oxide) were mixed with poly (methyl siloxane) (Rhodorsil 224). The mixtures were sprayed on silicon substrates resulting in the formation of a rough, two-length-scaled hierarchical structure surface layer. We report that: (i) Super-hydrophobic composite films were produced with all the particles used, (ii) The effect of the particle’...

The present study was carried out to investigate the antioxidant potential, total flavonoid and phenolic content in extracts of aerial parts of Cordia retua (Vahl.) Masam. The samples such as ethyl acetate and ethanol extracts were tested using six in vitro models such as 2,2-diphenyl-1-picrylhydrazyl, nitric oxide radical, iron chelating, hydroxyl radical, superoxide radical scavenging activit...

Despite the decrease in incidence observed during the last decades, gastric adenocarcinoma remains the fourth most common cancer in the world and the second leading cause of cancer-related death. Radical surgical resection is the best treatment option, though the role of extended and super-extended lymphadenectomy remains debatable. This review examines the different issues related to the surgi...