We consider maps on genus-$g$ surfaces with $n$ (labeled) faces of prescribed even degrees. It is known since work Norbury that, if one disallows vertices degree one, the enumeration such related to counting lattice point in moduli space curves labeled points and given by a symmetric polynomial $N_{g,n}(\ell_1,\ldots,\ell_n)$ face degrees $2\ell_1, \ldots, 2\ell_n$. generalize this restricting ...

FucP of Escherichia coli catalyzes L-fucose/H(+) symport, and a crystal structure in an outward-facing conformation has been reported. However, nothing is known about FucP conformational dynamics. Here, we show that addition of L-fucose to purified FucP in detergent induces ∼20% quenching of Trp fluorescence in a concentration-dependent manner without a shift in λ(max). Quenching is essentially...

Reduced responsiveness to positive stimuli is a core symptom of depression, known as anhedonia. In the present study, we assessed the expression of anhedonia in our chronic stress mouse model using a subset of read-out parameters. In line with this, we investigated in how far chronic stress would affect the facilitating effect of post-training self-administration of sugar, as we previously obse...

The results of some studies show that there are some psychological problems in people with diabetes, such as depression The effectiveness of Stress immunization teaching on reducing stressful psychological feelings, stress, self-negative labeling and lack of self confidence. In order to determine the effectiveness of stress immunization teaching on reducing stressful psychological feelings and ...

A total of 19 anthracycline derivatives were tested for their ability to interfere in vitro with the action of the human replicative DNA ligase. Only those with the sugar devoid of unmodified amino groups or with large configurational modifications were found to be inactive. Maximal inhibition of DNA-joining activity was found to require a 4'-deoxy-3'-amino sugar. Self-adenylation of DNA ligase...

To determine the relation of self-reported history of diabetes as well as baseline and in-treatment blood sugar to subsequent cardiovascular disease (CVD) in treated hypertensive patients, we assessed the experience of 6886 participants in a systematic treatment program. The presence or absence of a history of diabetes was known for all patients, who were then stratified into 3 groups according...