let $r$ be a 2-torsion free ring and $u$ be a square closed lie ideal of $r$. suppose that $alpha, beta$ are automorphisms of $r$. an additive mapping $delta: r longrightarrow r$ is said to be a jordan left $(alpha,beta)$-derivation of $r$ if $delta(x^2)=alpha(x)delta(x)+beta(x)delta(x)$ holds for all $xin r$. in this paper it is established that if $r$ admits an additive mapping $g : rlongrigh...

background: the fundamental principles of internal targeted alpha therapy for cancer were established many decades ago.the high linear energy transfer (let) of alpha radiation to the targeted cancer cellscauses double strand breaks in dna. at the same time, the short range radiation spares adjacent normal tissues. this targeted approach complements conventional external beam radiotherapy and ch...

TNFα is an inflammatory cytokine and the caspase and apoptotic processes can be activated by TNFα There are two classes of TNFα (solTNF and tmTNFα) which are important from the receptor aspect, so that solTNFα and tmTNFα can attach to the TNFR1, but tmTNFα just attaches to the TNFR2. Microglia cells are resident immune cells of the central nervous ...