Five new maleic and succinic acid derivatives were isolated from the mycelium of Antrodia camphorata. Their structures were determined by various spectroscopic means. Maleimide derivatives 2 and 3 showed appreciable cytotoxic activity against LLC cells.

The bacterium Actinobacillus succinogenes GXAS137, an efficient producer of succinic acid, was isolated from bovine rumen in Nanning, Guangxi Province, China. Here, we present the 2.3-Mb genome assembly of this strain, which consists of 2,314,479 bp (G+C content of 44.89%) with a circular chromosome, 2,235 DNA coding sequences, 57 tRNAs, and 15 rRNAs.

DEWAN [1938] and Adler et al. [1939] reported that certain enzyme preparations obtained from heart muscle bring about a reductive amination of ac-ketoglutaric acid. The hydrogen required in this reaction may be provided from other dehydrogenase systems via coenzyme I or II, especially from the ,-hydroxybutyric and i8ocitric dehydrogenases, according to the schemes: (1) ac-ketoglutaric acid+NH3+...

Chronic lead poisoning has traditionally been treated by parenteral agents. We present a case where a comparison of ethylene diaminetetra-acetic acid was made with 2,3-dimethyl succinic acid (DMSA) which has the advantage of oral administration associated with little toxicity and appeared to be at least as efficacious.

DL-Malic acid-grown cells of the yeast Hansenula anomala formed a saturable transport system that mediated accumulative transport of L-malic acid with the following kinetic parameters at pH 5.0: Vmax, 0.20 nmol.s-1.mg (dry weight)-1; Km, 0.076 mM L-malate. Uptake of malic acid was accompanied by proton disappearance from the external medium with rates that followed Michaelis-Menten kinetics as ...

The synthesis and characterization of mixed ligand complexes of Fe (III) with tartaric acid/succinic acid and heterocyclic amines. These complexes were characterized on the basis of elemental analysis, conductometric, magnetic measurements, UVvis, IR spectral studies. All the complexes were found electrolytic and paramagnetic in nature with high spin octahedral structure. The synthesized comple...