The Psychiatric Research Interview for Substance and Mental Disorders (PRISM) is a psychiatric diagnostic interview designed to diagnose DSM-IV substance and mental disorders in patients who abuse alcohol or drugs. Primary disorders tested in the DSM-III-R version of the interview showed improved reliability over existing instruments, and substantially improved reliability for major depressive ...

Morphine is a schedule II-controlled substance that used to allow the diminution of intra-operative, post-operative or chronic pain. However, its usage limited due addiction and overdose liabilities. was observed cause tolerance, dependence withdrawal in human. Justification: date lack scientific evidence morphine carried out by using specific single human neuroblastoma cell-line (SK-N-SH). The...

BACKGROUND The clinical and etiologic implications of comorbid psychiatric and substance-use disorders are relevant across countries and cultures. The DSM-IV now places greater emphasis on the clinical and research utility of the substance-induced disorders classification, and clarifies several important diagnostic issues specific to primary and substance-induced disorders. However, no research...

BACKGROUND Previous theory and research suggest links between substance use and externalizing behavior problems, but links between substance use and internalizing problems are less clear. The present study sought to understand concurrent links among diagnoses of substance use disorders, internalizing disorders, and behavior disorders at age 18 as well as developmental trajectories of illicit su...

N Engl J Med 2003;349:975-86. Copyright © 2003 Massachusetts Medical Society. rug addiction is a chronic, relapsing disorder in which compulsive drug-seeking and drug-taking behavior persists despite serious negative consequences. Addictive substances induce pleasant states (euphoria in the initiation phase) or relieve distress. Continued use induces adaptive changes in the central nervous syst...

The problem of substance abuse has shown an increase in quantity, quality, and rate distribution, both terms the number victims types abuse. World drug reports around 275 million people used drugs worldwide 2020. In Indonesia, there are 3.66 users 2021. When with stop taking have desire to take it again, is called craving phase. case a 36-year-old male Mental Behavioral Disorders Due Use Other ...

Nicotine may affect sleep by influencing sleep-regulating neurotransmitters. Sleep disorders can increase the risk for depression and substance dependency. To detect the influence of sleep disturbances on the effect of smoking cessation, we investigated polysomnographically (PSG) the sleep of smoking subjects during a period of smoking, during withdrawal and after a period of abstinence from ni...