BACKGROUND Hepatitis C virus (HCV) infection has been linked to lymphoproliferative disorders. Marginal zone B-cell lymphoma (MZL) represents one of the most frequent lymphoma subtypes associated with HCV infection. We describe an unusual subset of HCV-associated MZL characterized by subcutaneous presentation. MATERIALS AND METHODS A series of 12 HCV-positive patients presenting with subcutan...

Lichenoid and granulomatous dermatitis is a new entity which is histologically defined by a band like lymphocytic infiltration in the upper portion of the dermis with obscuring the dermoepidermal junction and accompanied by basal layer degeneration and granulomatous inflammation. Herein, we presented two Iranian women with similar cutaneous and histopathologic findings. Both patients had asympt...

the clinical and histological feature of 52 years old woman with erythema induratum are discribed the characteristic cutaneous lesions on the legs of middle-aged woman were violaceous, indurated nodules, 1 to 2 cm in diameter which were painful, occasionally ulcerated and could heal with scarring. the diagnosis was confirmed by a strongly positive tuberculin test, histologic feature and by clea...

case presentation we reported a 36-year-old man with alhe lesion on penis and discussed the clinical and histopathological features. conclusions when we have any dermal or subcutaneous lesion on genitalia, we can consider alhe in differential diagnosis. introduction angiolymphoid hyperplasia with eosinophilia (alhe) is a benign slow-growing vascular proliferation characterized by dome-shaped vi...

CASE REPORT A 29 year old man was first admitted to Matsunami General Hospital because of high fever and muscle pain of both lower legs, finally resulting in him being unable to walk. Painful multiple subcutaneous nodules of both lower legs and the left arm were seen. There was no history of trauma. Total leucocytes, erythrocyte sedimentation rate, and C reactive protein were raised. The serum ...

An 80-year-old, Chinese male presented with multiple nontender, nonpruritic, skin-coloured subcutaneous nodules over the chest, back, left flank, thigh and right forearm that developed course of 2 months (Figure 1). There was no surface change overlying edge slipped away when palpated between fingers (positive slip sign). He previously diagnosed stage IVB diffuse large B-cell lymphoma (DLBCL) g...

We report a case of segmental neurofibromatosis or type V neurofibromatosis, rare genetic disorder defined by limitation multiple macular cutaneous pigmentations “cafe-au-lait” (CAL) spots and/or neurofibromas to single, unilateral segment the body. A 34-year-old woman presented our Deparment with tender, subcutaneous, palpabale nodules arising from previous episiotomy scar 2 years postpartum. ...

OBJECTIVES To describe the unusual immunohistological characteristics of two pulmonary rheumatoid nodules showing ectopic lymphoid follicles and the features normally associated with rheumatoid synovial membrane, and to discuss the implications of this novel observation. METHODS Two formalin-fixed wax-embedded pulmonary rheumatoid nodules were processed for immunohistology. RESULTS The cent...